Results 81 to 90 of about 48,184 (314)

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

open access: yesAdvanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol   +18 more
wiley   +1 more source

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu   +10 more
wiley   +1 more source

Diving dangerously: Exploring human health and resource trade-offs of extreme dive profiles in a Caribbean dive fishery. [graduate project].

open access: yes, 2016
Dive fishers around the world employ compressed air diving to harvest marine living resources in the quest for livelihoods. Fishers can suffer catastrophic health consequences while targetting these fisheries resources that are in states of ...
Winkler, Nicolas
core  

Dive characteristics of fin whales (Balaenoptera physalus) instrumented with time-depth recorders off the Azores

open access: yes, 2022
We report dive data collected from 21 fin whales (Balaenoptera physalus) instrumented with time-depth recorders (TDRs) off the Azores (38° N 28° W) between April and September, from 2007 to 2017.
Prieto, Rui   +3 more
core   +1 more source

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

open access: yesAdvanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen   +8 more
wiley   +1 more source

Physiological, morphological, and ecological tradeoffs influence vertical habitat use of deep-diving toothed-whales in the Bahamas.

open access: yesPLoS ONE, 2017
Dive capacity among toothed whales (suborder: Odontoceti) has been shown to generally increase with body mass in a relationship closely linked to the allometric scaling of metabolic rates.
Trevor W Joyce   +7 more
doaj   +1 more source

Teaching physics, conservation laws first (Digital Aquarium Deep Dive)

open access: yes, 2015
Professor Eric Mazur discusses the unique architecture of this ground-breaking, introductory physics textbook; the conservation-laws-first approach, and results obtained with this book.
Eric Mazur
core  

Diversity Impact on Vaccine Equity (DIVE) in Sri Lanka November 2021

open access: yes, 2022
This submission includes English, Sinhala (එන්නත්කරණ සමානාත්මතාවය කෙරෙහි වාර්ගික විවිධත්වයේ බලපෑම: ‍නොවැම්බර් 2021), and Tamil ( இலங்கையில் சமத்துவமாக தடுப்பூசி வழங்குதல் சார்ந்த பல்வேறுபட்ட தாக்கங்கள்) versions of the bulletin.Covid-19 has shed light ...
Peiris, Mahoshadi
core  

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

open access: yesAdvanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng   +15 more
wiley   +1 more source

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