Results 231 to 240 of about 860,939 (358)
Discrete Bayesian Inference as a Structure of Paths. [PDF]
Popkov VV.
europepmc +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Weighted Chernoff Information and Optimal Loss Exponent in Context-Sensitive Hypothesis Testing. [PDF]
Kelbert M, Kalimulina EY.
europepmc +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Revised taxonomy reveals sustained introgression and secondary contact in ancient lake ricefishes. [PDF]
Yashima Y +11 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Integrative Taxonomy Reveals a Candidate Lineage Within the <i>Rhinolophus macrotis</i> Group. [PDF]
Cong J +10 more
europepmc +1 more source
This paper investigates the presence of sigma and beta convergence between the Polish subregions over 1995–2006. We verify for the absolute convergence, as well as for the convergence conditioned on the stock of physical capital, human capital and the ...
Herbst, Mikolaj, Wójcik, Piotr
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