Results 251 to 260 of about 1,557,512 (335)

Evolutionary genomics and divergence of Cacopsylla species with a special focus on the apple proliferation vectors Cacopsylla melanoneura and Cacopsylla picta. [PDF]

BMC Genomics
Ragionieri L, Serbina LŠ, Corretto E, Howie JM, Cruz F, Alioto TS, Zadra N, Weil T, Anfora G, Stauffer C, Ometto L, Rota-Stabelli O, Schuler H.   +12 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Phylogeography of Chinese White Pine Beetle <i>Dendroctonus armandi</i> (Coleoptera: Curculionidae: Scolytinae) in China. [PDF]

Genes (Basel)
Ning H, Deng R, Xiao K, Huang B, Cao Y, Wu Q.   +5 more
europepmc   +1 more source

The effects of climate change on the distribution of South American antbirds (Thamnophilus punctatus complex) as affected by niche divergences and contact zone interactions between species

, 2019
Erasmo Andrade da Silva, Helder Farias Pereira de Araújo, Alexandre Luis Padovan Aleixo, Alexandre Antonelli, Alexandre Mendes Fernandes   +4 more
openalex   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Ecological speciation in allopatry is rooted in older divergence. [PDF]

Proc Natl Acad Sci U S A
MacColl ADC.
europepmc   +1 more source

On α-z-Rényi divergence in the von Neumann algebra setting [PDF]

Shinya Kato
openalex   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Evolutionary insights from complete mitochondrial genomes of <i>Aedes albopictus</i> and <i>Culex pipiens molestus</i> (Diptera: Culicidae). [PDF]

Anim Cells Syst (Seoul)
Akintola AA, Hwang UW.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source