Results 151 to 160 of about 14,931,309 (280)

Phylogenetic relations among Mexican phlebotomine sand flies (Diptera: Psychodidae) and their divergence time estimation. [PDF]

PLoS One, 2023
Lozano-Sardaneta YN, Díaz-Cruz JA, Viveros-Santos V, Ibáñez-Bernal S, Huerta H, Marina CF, Mis-Ávila PC, Martínez-Burgos M, Torres-Monzón JA, Sánchez-Cordero V, Becker I.   +10 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Phylogeny, Divergence Time Estimation and Biogeography of the Genus Onnia (Basidiomycota, Hymenochaetaceae). [PDF]

Front Microbiol, 2022
Zhao H, Zhou M, Liu XY, Wu F, Dai YC.
europepmc   +1 more source

Divergence Between Parametric Income Distributions

Situations often arise in which we are interested in measuring divergence between distributions over time or across regions. This paper proposes an entropy measure of divergence and derives analytical expressions for several parametric distributions ...
Hajargasht, Gholamreza
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

exTREEmaTIME: a method for incorporating uncertainty into divergence time estimates. [PDF]

Biol Open, 2022
Carruthers T, Scotland RW.
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Leaf optical properties and photosynthesis of fern species with a wide range of divergence time in relation to mesophyll anatomy. [PDF]

Ann Bot, 2023
Hanba YT, Nishida K, Tsutsui Y, Matsumoto M, Yasui Y, Sizhe Y, Matsuura T, Kawaguchi Akitsu T, Kume A.   +8 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Taxonomy, Phylogeny, Divergence Time Estimation, and Biogeography of the Family Pseudoplagiostomataceae (Ascomycota, Diaporthales). [PDF]

J Fungi (Basel), 2023
Zhang Z, Liu X, Tao M, Liu X, Xia J, Zhang X, Meng Z.   +6 more
europepmc   +1 more source