Results 151 to 160 of about 325,578 (303)

Divergence time estimates of Triticeae species based on chloroplast sequences.

open access: yes, 2014
a. Divergence times of the species based on the strict clock method, using a substitution rate of 1.06E-3per base per million years calculated using PAUP and r8s programs over the selected 37 kb region of the chloroplast genome.
Natacha Senerchia (533190)   +6 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

How to Summarize Estimates of Ancestral Divergence Times

open access: yesEvolutionary Bioinformatics, 2008
The use of molecular sequence data has increased interest in trying to date evolutionary events, with researchers wanting both an estimate of the divergence time and a confidence interval for that estimate. However, two methodological issues have recently been raised with respect to precision of the estimates: (i) the time of the ancestral event is ...
openaire   +4 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Comparative Analysis of Mitogenomic and Nuclear Gene Data Reveals Phylogenetic Implications, Divergence Times, and Historical Biogeography in the Subfamily Pyrginae (Lepidoptera: Hesperiidae)

open access: yesEcology and Evolution
The subfamily Pyrginae sensu lato (Lepidoptera: Hesperiidae) represents a group of skipper butterflies, consisting of 1132 species in 153 genera and nine tribes.
Jintian Xiao   +4 more
doaj   +1 more source

Phylogeographic Analyses of the Viviparous Multiocellated Racerunner (Eremias multiocellata) in the Tarim Basin of China

open access: yesDiversity
The genealogical and geographical distribution of a species offers insights into its evolutionary narrative, encompassing its population dispersion, migration, adaptation, and speciation—key aspects for comprehending the genesis and sustenance of ...
Junzhe Zhang   +8 more
doaj   +1 more source

The effect of species divergence time on divergence-based ascertainment bias.

open access: yes, 2013
Coalescent simulation as in Figure 1 were performed, however a species divergence time was varied between 5 and 100 4Ne generations was used (see Figure 1 caption for simulation details).
Andrew D. Kern (248482)
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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