Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
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Phylogenomics, divergence time estimation, and biogeography of <i>Iris</i> species from Kazakhstan using plastome sequence analysis. [PDF]
Front Plant SciAlmerekova S +5 more
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The Implications of Incongruence between Gene Tree and Species Tree Topologies for Divergence Time Estimation. [PDF]
Syst Biol, 2022 Carruthers T +5 more
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
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Phylogeny, divergence time and historical biogeography of <i>Phanerochaete</i> (<i>Basidiomycota</i>, <i>Polyporales</i>), with a description of two new species in Korea. [PDF]
IMA FungusCho M +6 more
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Insights into the Deep Phylogeny and Novel Divergence Time Estimation of Patellogastropoda from Complete Mitogenomes. [PDF]
Genes (Basel), 2022 Feng J +6 more
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
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Dating Divergence Times in Phylogenies
, 2007 This thesis concerns different aspects of dating divergence times in phylogenetic trees, using molecular data and multiple fossil age constraints. Datings of phylogenetically basal eudicots, monocots and modern birds (Neoaves) are presented. Large phylograms and multiple fossil constraints were used in all these studies.
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Phylogenetic and Divergence Time Estimation of Muscomorpha with Low-Coverage Whole-Genome Sequencing of Syrphidae (Diptera: Brachycera). [PDF]
Biology (Basel)Liao C, Li H, Gao Z, Yan W, Ji Y.
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Accounting for Errors in Data Improves Divergence Time Estimates in Single-cell Cancer Evolution. [PDF]
Mol Biol Evol, 2022 Chen K +4 more
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