Results 181 to 190 of about 14,940,574 (282)

Insights into the Deep Phylogeny and Novel Divergence Time Estimation of Patellogastropoda from Complete Mitogenomes. [PDF]

Genes (Basel), 2022
Feng J, Miao J, Ye Y, Li J, Xu K, Guo B, Yan X.   +6 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

High-quality assembly of the Chinese white truffle genome and recalibrated divergence time estimate provide insight into the evolutionary dynamics of Tuberaceae. [PDF]

Genome Res
Martelossi J, Vujovic J, Huang Y, Tatti A, Xu K, Puliga F, Chen Y, Rota Stabelli O, Ghiselli F, Zhang X, Zambonelli A.   +10 more
europepmc   +1 more source

Accounting for Errors in Data Improves Divergence Time Estimates in Single-cell Cancer Evolution. [PDF]

Mol Biol Evol, 2022
Chen K, Moravec JC, Gavryushkin A, Welch D, Drummond AJ.   +4 more
europepmc   +1 more source

New Inequalities for Jeffreys Divergence Measure

, 2015
[[abstract]]The problem of choosing a proper divergence measure is an important one. We provide new inequalities involving Jeffreys, triangular and other divergence measure in Information ...
Dragomir,S. S., Buse,C., Sunde,J.
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

The Genetic Diversity and the Divergence Time in Extant Primitive Mayfly, Siphluriscus chinensis Ulmer, 1920 Using the Mitochondrial Genome. [PDF]

Genes (Basel), 2022
Tong Y, Shen CY, Zhao YY, Lin YJ, Wu L, Storey KB, Yu DN, Zhang JY.   +7 more
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Assessing the Population Demographic History of the Tsushima Leopard Cat and Its Genetic Divergence Time from Continental Populations. [PDF]

Biology (Basel)
Ito H, Nakajima N, Onuma M, Kishida T, Inoue-Murayama M.   +4 more
europepmc   +1 more source

Genomes of single- and double-petal jasmines (Jasminum sambac) provide insights into their divergence time and structural variations. [PDF]

Plant Biotechnol J, 2022
Wang P, Fang J, Lin H, Yang W, Yu J, Hong Y, Jiang M, Gu M, Chen Q, Zheng Y, Liao Z, Chen G, Yang J, Jin S, Zhang X, Ye N.   +15 more
europepmc   +1 more source