Results 81 to 90 of about 1,302,629 (287)

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

Divergent thinking and stress dimensions

open access: yes, 2015
This study examines the role of the stress state dimensions of Engagement, Distress, and Worry before and during a divergent thinking (DT) task, while controlling for trait emotional intelligence (trait EI).
Sanchez-Ruiz, Maria-José   +4 more
core   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

METHODOLOGY FOR DEVELOPING DIVERGENT THINKING OF PRIMARY SCHOOL PUPILS

open access: yes, 2023
This article talks about the formation of divergent thinking of primary education ...
Xo’jamberdiyeva Sarvinoz Keldiyarovna
core  

Semantic Retrieval Strategies in Divergent Thinking

open access: yes, 2023
In this study we investigate semantic retrieval strategies in order to inform discussions about cognitive mechanisms underlying divergent thinking and creativity. Relying on a verbal fluency task, we map the particular associative strategies participants engage and how they predict their performance.
Kuczma, Urszula   +2 more
openaire   +3 more sources

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

Divergent Thinking about Objects in the Grasslands of Curiosity.

open access: yes, 2017
The current study investigates if and how curiosity can influence divergent thinking about objects when processing information for survival relevance.

core   +3 more sources

The Effect of First and Second Language Use on Divergent Thinking in Problem Solving

open access: yesCERN IdeaSquare Journal of Experimental Innovation
This study aims to explore the relationship of the language used when solving a problem, and the creative ability to find a solution for it. For this, participants completed a task in their first language, and a similar task in their second language and ...
Sofia Calvo, Jop Goekoop
doaj   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs   +7 more
wiley   +1 more source

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