Results 111 to 120 of about 16,994 (249)

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

Study of Single Null divertor in DTT with Nitrogen, Neon and Argon seeding

, 2019
The EUROfusion roadmap [1] has recognized the exhaust of large heat loads as one of the most critical issue to solve for the generation of electrical power with a Demonstration Fusion Power Plant (DEMO) by 2050. This condition is particularly challenging
Innocente P, Balbinot L, Subba F, Rubino G, Calabró G   +4 more
core  

A New Ordered Transformation‐Induced Plasticity Enables Exceptional Strength and Ductility in a B2 Medium‐Entropy Alloy

Advanced Science, EarlyView.
A novel B2‐ordered Ti‐Zr‐V‐Al medium‐entropy intermetallic is developed through controlled metastability engineering, which activates an ordered TRIP effect via a new B2→D019‐α2 transformation with a distinctive {0001}α2//{110}B2, <11‐20>α2//<100>B2 orientation relationship. This alloy achieves an elongation of ∼7%, a strength of ∼1.1 GPa, and superior
Chaohua Li, Yidong Wu, Boyuan Zheng, Xu Zhang, Xiongjun Liu, Wenli Song, Ning An, Chengbo Xiao, Xidong Hui   +8 more
wiley   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Depth‐to‐Areal Staging Heterogeneity Preceding Lithium Plating in Graphite Anodes Revealed by Operando Imaging

Advanced Science, EarlyView.
Fast charging drives graphite anodes far from equilibrium, yet where lithium plating begins has remained hidden. Operando optical microscopy here reveals that neighboring regions advance through the staging sequence asynchronously, and that domains reaching advanced lithiation earliest become the preferential sites where plating initiates.
Tae Young Choi, Juyoung Kim, Vithiya Muralidharan, Seungwoo Choi, Jeongwoo Seo, Seungwoo Ryu, Myeongjun Choi, Hyun‐Wook Lee   +7 more
wiley   +1 more source

Snowflake divertor configuration studies for NSTX-Upgrade [PDF]

, 2011
Snowflake divertor experiments in NSTX provide basis for PMI development toward NSTX-Upgrade. Snowflake configuration formation was followed by radiative detachment. Significant reduction of steady-state divertor heat flux observed in snowflake divertor.
Soukhanovskii, V A
core  

In Situ CO2‐Induced Hydrogels for Enhancing Carbon Sequestration in Saline Aquifers

Advanced Science, EarlyView.
A novel integrated method that combines in situ CO2‐induced phase‐transition hydrogels formed by a C22‐tailed tertiary amine dispersion with tailored deep eutectic solvents to increase CO2 sequestration in saline aquifers. ABSTRACT Carbon sequestration in saline aquifers underpins global net‑zero emission goals, yet existing CO2 storage capacity ...
Fuchuan Liu, Xinjie Luo, Dianguo Wu, Xuezhi Zhao, Yan Zhang, Yujun Feng   +5 more
wiley   +1 more source

On the Use of CX Atom Analyzer for Study Characteristics of Ion Component in a LHD Divertor Plasma

, 1996
"In this paper the analysis was provided for the possibility to use the charge exchange atom analyzer using the ion reflection phenomena on solid surtfaces for measuring the characteristics of the ion component of a divertor plasma in LHD. As an ion-atom
Noda, N., "Voitsenya, V.S., Motojima, O., Ohyabu, N.", Masuzaki, S.   +4 more
core  

Bio‐Inspired Gradient Heterogeneous Architectures for Ultrasensitive and Robust Strain Sensors via Programmable Crack Engineering

Advanced Science, EarlyView.
Inspired by the insect campaniform sensillum, a heterogeneous bilayer strain sensor is developed based on a unique impedance mismatch and three‐dimensional structural dynamic percolation strategy. The sensor enables real‐time multi‐joint teleoperation of three joints and the gripper using a six‐degree‐of‐freedom robotic‐arm platform.
Qi Wu, Tiantong Wang, Yinhao Wang, Yanggang Feng, Yan Huang   +4 more
wiley   +1 more source

Implementation of a tightly baffled long-legged divertor in TCV

Nuclear Fusion
The TCV tokamak contributes to the development of nuclear fusion energy with proof-of-principle experiments and by challenging models that are used to predict reactor performance.
H. Reimerdes, O. Février, C. Theiler, H. Elaian, Y. Andrebe, B. Brown, R. Ducker, G. Durr-Legoupil-Nicoud, B.P. Duval, D. Mykytchuk, A. Perek, U. Sheikh, P. Sintre, E. Tonello, B. Vincent, the TCV Team   +15 more
doaj   +1 more source