Results 61 to 70 of about 4,897,555 (276)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Local Convergence Analysis of an Eighth Order Scheme Using Hypothesis Only on the First Derivative

open access: yesAlgorithms, 2016
In this paper, we propose a local convergence analysis of an eighth order three-step method to approximate a locally unique solution of a nonlinear equation in a Banach space setting. Further, we also study the dynamic behaviour of that scheme.
Ioannis K. Argyros   +2 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

How to Disagree: Negotiate Difference in a Divided World, by Adam Ferner and Darren Chetty

open access: yesJournal of Philosophy in Schools, 2020
In writing 'How to Disagree', Ferner and Chetty aim to bring to light those assumptions we make about the world, its structure and the lived reality of what we assume to be real, in order to see how these assumptions affect the ways we engage with each ...
Elizabeth O'Brien
doaj   +1 more source

Effects of intrathecal opioids use in cesarean section on breastfeeding and newborns’ weight gaining [PDF]

open access: yes, 2016
Objective: To assess the association between intrapartum intrathecal opioid use and breastfeeding and weight gain following cesarean section. Materials and methods: The prospective double-blinded study was conducted on term pregnant women, undergoing ...
Anbarafshan, Mohammad   +6 more
core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

The effect of spatial learning on the number of astrocytes in rat dentate gyrus [PDF]

open access: yes, 2007
In this study, we evaluated the effect of spatial learning on the number of astrocytes in the rat dentate gyrus with Morris water maze. Fifteen male albino Wistar rats were divided into three groups as control, reference memory and working memory groups.
Hosseini, A.   +3 more
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Use of identity of A. Hurwitz for construction of a linear positive operator of approximation

open access: yesJournal of Numerical Analysis and Approximation Theory, 2002
By using a general algebraic identity of Adolf Hurwitz [1], which generalizes an important identity of Abel, we construct a new operator \(S_m^{(\beta_1,\ldots,\beta_m)}\) approximating the functions. A special case of this is the operator \(Q_m^\beta\)
Dimitrie D. Stancu
doaj   +2 more sources

Blood pressure response to Cold Pressor Test in the children of hypertensives [PDF]

open access: yes, 2010
Two hundred student volunteers of 16-24 yrs were divided into two groups of 100 each, as children of hypertensive and children of normotensive parents. It was observed that there was no difference in resting SBP and DBP in both groups before CPT.
Garg, S, Kumar, A, Singh, KD
core   +1 more source

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