Results 81 to 90 of about 1,768,757 (251)
On Hermite interpolation and divided differences
Summary: This paper is a survey of topics related to Hermite interpolation. In the first part we present the standard analysis of the Hermite interpolation problem. Existence, uniqueness and error formula are included. Then some computational aspects are studied including Leibnitz' formula and devided differences for monomials.
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On an iterative Moser-Kurchatov method for solving systems of nonlinear equations
This paper is devoted to analysis of an iterative method for solving nonlinear equations. The method, inspired by the Kurchatov-type methods, is specifically designed to avoid the need for derivative calculations or inverses of linear operators.
I. K. Argyros +2 more
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Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
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Reliable road traffic state identification systems should be designed to provide accurate traffic state information anywhere and anytime. In this paper we propose a road traffic classification system, based on traffic variables estimated using the second
Ouessai Asmâa, Keche Mokhtar
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
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Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Multivariate Divided Differences. I: Basic Properties
Within the theory of spline functions, there is always great interest in divided differences, since they provide one possibility to define \(B\)- splines, i.e. splines with minimal support. In the paper under consideration, which is part of the author's doctoral thesis, a new type of generalization of the univariate divided differences to the ...
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Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
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