Results 71 to 80 of about 5,042,272 (275)

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

open access: yes
Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra   +9 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Use of identity of A. Hurwitz for construction of a linear positive operator of approximation

open access: yesJournal of Numerical Analysis and Approximation Theory, 2002
By using a general algebraic identity of Adolf Hurwitz [1], which generalizes an important identity of Abel, we construct a new operator \(S_m^{(\beta_1,\ldots,\beta_m)}\) approximating the functions. A special case of this is the operator \(Q_m^\beta\)
Dimitrie D. Stancu
doaj   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Local Convergence Analysis of an Eighth Order Scheme Using Hypothesis Only on the First Derivative

open access: yesAlgorithms, 2016
In this paper, we propose a local convergence analysis of an eighth order three-step method to approximate a locally unique solution of a nonlinear equation in a Banach space setting. Further, we also study the dynamic behaviour of that scheme.
Ioannis K. Argyros   +2 more
doaj   +1 more source

Quasisymmetric divided differences

open access: yes
We develop a quasisymmetric analogue of the combinatorial theory of Schubert polynomials and the associated divided difference operators. Our counterparts are "forest polynomials", and a new family of linear operators, whose theory of compositions is governed by forests and the "Thompson monoid".
Nadeau, Philippe   +2 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

How to Disagree: Negotiate Difference in a Divided World, by Adam Ferner and Darren Chetty

open access: yesJournal of Philosophy in Schools, 2020
In writing 'How to Disagree', Ferner and Chetty aim to bring to light those assumptions we make about the world, its structure and the lived reality of what we assume to be real, in order to see how these assumptions affect the ways we engage with each ...
Elizabeth O'Brien
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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