Results 111 to 120 of about 3,221,811 (296)
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Divine Action in the World of Physics: Response to Nicholas Saunders
Zygon, 2000 Nicholas Saunders claims that, in my view, divine action requires and is confined to indeterminacies at the quantum level. I try to make clear that, in speaking of “gaps” in physical causality, I mean that the existence of intentions entails that ...
doaj +2 more sources
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
God, time and eternity: philosophical foundations for a defence of divine timelessness [PDF]
, 2007 The past two decades have seen an almost exponential growth in publications on the topic of divine eternity and the general area of 'God and time'. Increasing appeal is made to arguments and resources which ranges widely through contemporary science and ...
Foyle, Stuart Mark
core
Considering the Place of Apophaticism within Science-Engaged Theology
ZygonDespite its firm embeddedness in the Christian tradition, apophatic theology has been strangely absent in the science-and-religion dialogue. Given that the apophatic theologian eschews the idea that we can fully comprehend God, or positively articulate ...
Mikael Leidenhag
doaj +2 more sources
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
A HEURISTIC SCIENCE‐BASED NATURALISM AS A PARTNER FOR THEOLOGICAL REFLECTIONS ON THE NATURAL WORLD
Zygon, 2015 After a few general observations on scientific activity, the author briefly comments on different versions of naturalism. Subsequently, he suggests that the birth of evolutionary biology and its successive developments may show how the natural world ...
doaj +2 more sources