Results 111 to 120 of about 3,124,156 (300)

Does academic stress predict nursing students' healthy and unhealthy behaviour? [PDF]

open access: yes
The study aimed to examine the effect of academic stress on the healthy and unhealthy behaviour of nursing students. To gain more understanding of the concepts, literatures were reviewed.
Quinto, Egdonna, Egdonna A., Quinto
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

A HEURISTIC SCIENCE‐BASED NATURALISM AS A PARTNER FOR THEOLOGICAL REFLECTIONS ON THE NATURAL WORLD

open access: yesZygon, 2015
After a few general observations on scientific activity, the author briefly comments on different versions of naturalism. Subsequently, he suggests that the birth of evolutionary biology and its successive developments may show how the natural world ...
doaj   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

ISLAM AND SCIENCE: THE NEXT PHASE OF DEBATES

open access: yesZygon, 2015
This article reviews the new developments that have occurred in the past ten to fifteen years in the field of Islam and science: (1) the emergence of a “new generation” of thinkers, Muslim scientists who accept modern science's fundamental methodology ...
doaj   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

THE DIVINE SPIRIT AS CAUSAL AND PERSONAL

open access: yesZygon, 2013
Theists in general and Christians in particular have good grounds for affirming divine action in relation to twenty‐first‐century science. Although humans cannot perceive with their five senses the causation—both divine and creaturely—at work in our ...
doaj   +2 more sources

A School’s Own Adaptation of Action Learning: From a Traditional Action Learning Project, to a Whole School Action Learning Project, to a Professional Learning Culture.

open access: yes, 2017
Action Learning finds its basis in experimental learning theory. For the staff at Western Public school Action Learning and experimental learning underpin their success of the use of Action Learning within their school.
Mehorter, Bronwyn Ruth
core  

Tapes from the Divine Word University in Madang

open access: yes
Tapes from the Divine Word University in Madang, PNG, including Fr.

core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

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