Results 121 to 130 of about 348,820 (310)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Providence as “Responsible Risk-Taking”

open access: yesTheoLogica
This paper explores the concept of divine providence in the framework of open theism, focusing on the balance between God’s sovereignty and creaturely libertarian free will.
Johannes Grössl
doaj   +1 more source

The Evolution of Consciousness and God's Action in the World [PDF]

open access: yes, 2012
This study, based on the works of Teilhard de Chardin, Karl Rahner, Karl Schmitz- Moormann, and George Ellis, analyzes how consciousness has followed an evolutionary process that has made possible the appearance of human beings in the Creation.
Pérez, Noemí
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Camping with Jesus: Theologically Reflecting on Evangelical Christian Festivals

open access: yesReligions
Attending a Christian summer camp or festival is a regular feature of many evangelical church calendars within the UK. This article uses a practical theology approach to explore definitions and distinctives of evangelical camping, both within the ...
Helen Collins
doaj   +1 more source

\u27Yes!\u27 and \u27thou\u27 in Dag Hammarskjold\u27s Markings : A theological investigation [PDF]

open access: yes, 2016
Hammarskjöld’s Markings combines the spiritual, theological and ethical. This article engages with the journal in four stages. First, it briefly introduces the text (context, translation and overall purpose). Second, I explore Hammarskjöld’s faith guided
Ryan, T
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Contemporary Aristotelian–Thomistic Perspective on the Evolutionary View of Reality and Theistic Evolution

open access: yesReligions
This article presents a coherent and comprehensive proposal of a renewed contemporary Aristotelian–Thomistic approach to the evolutionary view of reality and the position of theistic evolution.
Mariusz Tabaczek
doaj   +1 more source

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