Results 31 to 40 of about 5,888,690 (275)
A Study and Explanation of the Theory of General Justice in the View of St. Thomas Aquinas [PDF]
Pizhūhish/hā-yi Falsafī- Kalāmī, 2020 General Justice is a virtue that leads people to the community order and goods through which they can achieve well-being. This article explains the theory of general justice from the perspective of Aquinas and examines the common good and its role as the
Abdollah Abedifar, Mohsen Javadi
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Divine Commands or Divine Attitudes? [PDF]
, 2013 In this essay, I present three arguments for the claim that theists should reject divine command theory in favor of divine attitude theory. First, DCT implies that some cognitively normal human persons are exempt from the dictates of morality. Second, it
Jordan, Matthey Carey +1 more
core +3 more sources
Normative Reasons, Epistemic Autonomy, and Accountability to God
Religions, 2023 According to many, human autonomy is necessary for moral action and yet incompatible with being morally accountable to God’s divine commands. By issuing commands that ground normative facts, God demands our accountability without understanding our ...
Brandon Rickabaugh
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Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Virtue Depends on Natural Law and Divine Commands
ReligionsVirtue theory has occupied a place of relative prominence within the Christian intellectual tradition. But there is a problem facing it: how one contemplates the virtues and vices will ultimately depend upon deeper accounts of the good and the right ...
J. Caleb Clanton, Kraig Martin
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Can Ethics Exist Without God? A Thomistic Critique of James Sterba’s Axiomatic Morality
ReligionsThis essay explores the question: can we have an objective ethics without God? This question is raised by James Sterba, who argues in the affirmative. As an atheistic ethicist, Sterba is motivated to maintain an objective morality that is not based in ...
Joseph Brian Huffling
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