Results 41 to 50 of about 147,317 (313)

The two levels of natural law thinking [PDF]

open access: yes, 2015
Central parts of the natural law theories of Grotius and Pufendorf assume that persons by nature have individual realms of their own (suum), violations of which constitute a wrong. This is the basis for their accounts of promises, ownership and reactions
Mautner, Thomas, Olivecrona, Karl
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Normative Reasons, Epistemic Autonomy, and Accountability to God

open access: yesReligions, 2023
According to many, human autonomy is necessary for moral action and yet incompatible with being morally accountable to God’s divine commands. By issuing commands that ground normative facts, God demands our accountability without understanding our ...
Brandon Rickabaugh
doaj   +1 more source

What if God commanded something horrible? A pragmatics-based defence of divine command metaethics [PDF]

open access: yes, 2021
The objection of horrible commands claims that divine command metaethics is doomed to failure because it is committed to the extremely counterintuitive assumption that torture of innocents, rape, and murder would be morally obligatory if God commanded ...
Kremers, Philipp
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Virtue Depends on Natural Law and Divine Commands

open access: yesReligions
Virtue theory has occupied a place of relative prominence within the Christian intellectual tradition. But there is a problem facing it: how one contemplates the virtues and vices will ultimately depend upon deeper accounts of the good and the right ...
J. Caleb Clanton, Kraig Martin
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Taking God Seriously, but Not Too Seriously: The Divine Command Theory and William James' 'The Moral Philosopher and the Moral Life’ [PDF]

open access: yes, 2013
While some scholars neglect the theological component to William James’s ethical views in “The Moral Philosopher and the Moral Life,” Michael Cantrell reads it as promoting a divine command theory (DCT) of the foundations of moral obligation.
Boone, Mark J.
core  

"... in God only one infinite act can be thought...": The Ambiguity of Divine Agency and the Diversity of Evil [PDF]

open access: yes, 2015
The paper argues that God does not act but is creative activity, which helps to overcome evil by the possibilities of the good that it opens up for creatures in the face of ...
Dalferth, Ingolf U.
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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