Results 51 to 60 of about 4,303,518 (344)
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
THE DIVINE LIGHT. THE SIGHT AND EXPERIENCE OF IT IN GREGORY PALAMAS THEOLOGY
Astra Salvensis, 2019 In the paper, the authors focused Gregory Palamas theology regarding the divine light which he had developed during the hesychast controversy that occurred in the 14th century. Palamas entered in an intellectual debate with his adversary Barlaam with the
Ioan Chirilã +3 more
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Love and Friendship in the Lysis and the Symposium: Human and Divine [PDF]
, 2008 The paper claims that we cannot understand properly Platonic conception of love and friendship unless we read the Lysis in the light of the Symposium and vice verse.
Jinek, Jakub
core
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Divine love in the letter to the Romans
In die Skriflig, 2016 This article investigates divine love in the letter to the Romans from the perspective of love as a key motif in spirituality and in light of spiritual hermeneutics.
Pieter G.R. de Villiers
doaj +1 more source
, 2012 Leon Battista Alberti and Marsilio Ficino, though separated by twenty-nine years in age, had a close relationship as mentor and pupil. Concepts which can be found in Alberti’s De pictura (1435) and De re aedificatoria (1450) are infused in Ficino’s De ...
Hendrix, John S
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
PHILOSOPHICAL AND RELIGIOUS ORIGINS OF THE PRIVATE INNER SELF
Zygon, 2011 . The modern concept of the inner self containing a private inner world has ancient philosophical and religious roots. These begin with Plato's intelligible world of ideas.
doaj +2 more sources