Results 61 to 70 of about 4,303,518 (344)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Reflections on God and Evil in the Krishna Bhakti Theology of Caitanya [PDF]

open access: yes, 2016
The story that forms the short prologue at the start of Valmiki’s Rāmāyana expresses something of how the bhakta deals with tragic loss and senseless violence.
Schweig, Graham M.
core   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Missional Churches in Secular Societies: Theology Consults Sociology [PDF]

open access: yes, 2011
The church is missionary by nature. But what about public church mission in secular societies? Furious religion mobilizing against rebarbative secularity? Withdrawal to seek exemplary perfection?
Hughson, Thomas
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Reading a Protoevangelium in the Context of Genesis [PDF]

open access: yes, 2014
This article proposes that the case for a ‘messianic’ reading of Gen. 3:15 is cumulative. No single individual argument is decisive and it is virtually impossible to sustain a robust protevangelium interpretation of this text within the context of Gen. 3
Pettus, David
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

FALSIFIABILITY AND TRACTION IN THEORIES OF DIVINE ACTION

open access: yesZygon, 2010
One of the most focused research programs in the science‐religion dialogue that has taken place up to the present is the series of volumes published jointly by the Vatican Observatory and the Center for Theology and the Natural Sciences.
doaj   +2 more sources

The Gods of My Father Terah’: Abraham the Iconoclast and the Polemics with the Divine Body Traditions in the Apocalypse of Abraham [PDF]

open access: yes, 2008
The first eight chapters of the Apocalypse of Abraham recount the early years of the young hero of the faith who is depicted as a fighter against the idolatrous practices of his father Terah. The conceptual developments found in this section of the work,
Orlov, Andrei
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

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