Results 101 to 110 of about 223,708 (309)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The Redemptive Act of Reading: Richard Crashaw & the Teresean Liturgy [PDF]
, 2012 The essay entitled “The Redemptive Act of Reading: Richard Crashaw and the Teresean liturgy” written by Alexandra Finn-Atkins is centered on Richard Crashaw’s trilogy of poems dedicated to the sixteenth century Saint Teresa of Ávila. The trilogy consists
Finn-Atkins, Alexandra
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Reading a Quaker\u27s Book: Elizabeth Ashbridge\u27s Testimony of Quaker Literary Theory
, 2014 Elizabeth Ash bridge offers one of the most striking transatlantic spiritual autobiographies of the eighteenth century. While historians and scholars alike have given careful attention to this now-canonical text, no one to date has yet positioned this ...
Tarter, Michele L.
core
From Yeezus to Pablo: An Existential Theology between God, Blackness, and Being [PDF]
, 2018 Kanye West has transformed and transfigured from a young rapper representing the Southside of Chicago, to an icon, a rap genius, a god. His persona has continually evolved from his arrival on the Hip Hop scene, leading to his emergence as, Yeezus. This
Watts, Shea
core +1 more source
Roczniki Teologiczne, 2016 The article is an analysis of the proclamation delivered to the Church through St. Faustina in respect of God's calls contained in it. First, based on the picture of Jesus Merciful, it is inferred that there is a call to trust in God's Goodness and Mercy, to repent, to convert and accept the forgiveness of sins in the sacrament of penance and ...
openaire +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source