Results 91 to 100 of about 223,708 (309)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

"قرآن مجید بطور معجزاتی چیلنج: قدیم و جدید آراء کا تقابل The Miraculous Nature of Quran as a challenge: A comparative Study of Ancient and Modern Opinions "

open access: yesالإيضاح, 2017
Almighty Allah created the man, endowed him with intellect and raised prophets among humanity for guidance. The scriptures were revealed by him which contained Divine commandments.
Ghulam Mustafa , Ehsan ur Rahman Ghouri
doaj  

Ethics and Aesthetics in the Song of Songs

open access: yesTyndale Bulletin, 1994
While readings of the Song of Songs tend to focus on the extent of its licencing of pre-marital sex, the Song’s message on the nature of sexual and human loving is to be found in its choice of metaphors for that activity.
Mark W. Elliott
doaj   +1 more source

Świadectwo Boga Ojca o Jezusie w Ewangelii wg św. Jana

open access: yesVerbum Vitae, 2015
The article addresses the issue of the witness of the Father about Jesus in the Fourth Gospel. The topic is inscribed in the very essential theological message of the Gospel of John, according to which Jesus is the Messiah and the Son of God revealing ...
Janusz Kręcidło
doaj   +1 more source

Chapitre 2. Messagers divins et démon tentateur

open access: yes, 2007
I. Jésus-Christ et les anges1. Jésus-ChristLes Songes Daniel ne font pas allusion à Jésus. Quant à la clef d’Achmet, ce n’est qu’après les visions d’anges, de prophètes, d’apôtres et d’hommes d’Église qu'elle fait mention d’apparitions de Jhesucrist.
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Emblematic Arches – Contributions to Reading a Hapsburg Festival [PDF]

open access: yes, 2016
In 1619 Philip III of Spain (II of Portugal) enters into Lisbon, in what was to be the culmination of a long awaited and extensively planned royal entrée into his Portuguese kingdom, in the context of the Iberian Dual Monarchy.
Gomes, Luis
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The American Nightmare: The Ford Edsel Flop and Sputnik Terror [PDF]

open access: yes, 2016
During the late 1950s, it seemed everyone was pelting Ford Motor Company’s ill-fated Edsel. What was supposed to be the car of the future and an emblem of American prestige had turned into a symbol of America’s sharp decline.
Moran, Nicholas
core   +1 more source

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