Results 71 to 80 of about 553,317 (257)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Tapes from the Divine Word University in Madang

Tapes from the Divine Word University in Madang, PNG, including Fr.

core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Prophecy In Later Islamic Thought: The Mystical Views of Shah Waliyyullah Ad-Dihlawi

Tsaqafah, 2009
Scholarly interest in the thought and teachings of Shâh Waliyyullâh adDihlawî has increased in recent years –not surprisingly, given the richness and profundity of his writings.
Syamsuddin Arif
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Letter from W. Divine and T. G. Ferrclo, Sycamore, Illinois, to S. E. Jones, Iowa Falls, Iowa, October 1, 1883

, 1883
Letter from Divine and Ferrclo in Sycamore, Illinois, to S. E. Jones in Iowa Falls, Iowa.
Ferrclo, T. G., Divine, W.
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Investigating the influence of bureaucratic and humanistic work environment on the employees’ work ethics: Management

The study aimed to investigate the effect of bureaucratic and humanistic work environments on the work ethics of the employees. To deepen the concepts, the literature was reviewed. The study used the assessment and correlational research design.
Cabillo, Edna, Martin, Kristina, Cabillo , Edna R., Basilio, Gladys Jean Q., Julian, Fredolin, Martin , Kristina O.   +5 more
core   +1 more source

Fear, threat and efficacy in threat appeals: message involvement as a key mediator to message acceptance

, 2009
: In a sample of 170 youngsters, the effect of two versions of a public service announcement (PSA) threat appeal against speeding, placed in four different contexts, on evoked fear, perceived threat (severity and probability of occurrence), perceived ...
Dens, Nathalie, Cauberghe, VerolinePS018020004111730000-0003-0713-8486FB46B406-F0ED-11E1-A9DE-61C894A0A6B4, De Pelsmacker, Patrick, Dens, N.editor, Cauberghe, Veroline, Janssens, Wim, Cauberghe, Verolien, De Pelsmacker, PatrickUGent801001018254973488797582F4E8B2F8-F0ED-11E1-A9DE-61C894A0A6B4, De Pelsmacker, P.editor   +8 more
core   +1 more source

Il ruolo della Legge Divina nel sistema dei valori cristiano antico

CoSMO, 2013
The essay examines the argumentative and hermeneutical strategies by which Early Christianity adapted concepts and notions borrowed from the past to the Gospel message.
Giovanni Filoramo
doaj   +1 more source