Results 41 to 50 of about 130,885 (293)

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

The Image of an Architect and Masonic Symbols in Works by Milorad Pavić

open access: yesRespectus Philologicus, 2021
The paper analyzes works by the Serbian postmodernist writer Milorad Pavić. It attempts to prove that he possesses knowledge of royal art and uses masonic symbols in his writing related to geometry and architecture, including the radiant delta, compass ...
Zoriana Huk
doaj   +1 more source

Metaphor, religious language and religious experience [PDF]

open access: yes, 2007
Is it possible to talk about God without either misrepresentation or failing to assert anything of significance? The article begins by reviewing how, in attempting to answer this question, traditional theories of religious language have failed to ...
Harrison, V.S.
core   +1 more source

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich   +5 more
wiley   +1 more source

Philibert Delorme’s Divine Proportions and the Composition of the Premier Tome de l’Architecture

open access: yesArchitectural Histories, 2014
In his 'Premier tome de l’architecture' (1567) — the first original, comprehensive architectural treatise written by a French author — Philibert Delorme (c. 1514–1570) claims to be the first to formulate a theory of divine proportions, which he describes
Sara Galletti
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Conceptual Coherence in Bagarah Surah Based on the Concepts of Prophecy and the Opponents of the Truth [PDF]

open access: yesپژوهش نامه معارف قرآنی, 2018
One the highly debatable issues between Muslim scholars and orientalists is the conceptual coherence between verses in the holy Quran. The proportion of verses of the holy Quran as a form of knowledge attracted the attention of Islamic scholars. In order
mehdi asmaili sadrabadi, tahere nowbaghi
doaj   +1 more source

Spinoza and the problem of other substances [PDF]

open access: yes, 2019
Most of Spinoza’s arguments for God’s existence do not rely on any special feature of God, but instead on merely general features of substance. This raises the following worry: those arguments prove the existence of non-divine substances just as much as ...
Barry, Galen
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Simone Weil\u27s Spiritual Critique of Modern Science: An Historical-Critical Assessment [PDF]

open access: yes, 2008
This paper evaluates Simone Weil\u27s philosophy and theology of science from the perspective of an historical phenomenology of ...
Cosgrove, Joseph K.
core   +1 more source

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