Results 51 to 60 of about 130,885 (293)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The golden ratio—dispelling the myth

Maxillofacial Plastic and Reconstructive Surgery
Background The purpose of this article is to explore the claims often cited in scientific journals regarding the golden ratio, and its proposed link to beauty and idealized forms in nature, including idealized human proportions.
Farhad B. Naini
doaj   +1 more source

Geometry of an English Church Bell

Encyclopedia
The axisymmetric geometries of both internal and external profiles of church bells, along with the properties of the bell metal, are of vital importance to their acoustics.
Robert Perrin, Zimu Guo, David Eager, Benjamin Halkon   +3 more
doaj   +1 more source

Divining Proportions in the Information Age

Architectural Histories, 2014
The process of reverse engineering proportional systems of historic buildings has long been fraught with problems. One cannot assume, without knowing the specific conditions of acquisition, that existing plans are accurate enough to sustain the scrutiny necessary to resolve differences among potential proportional schemes.
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Anthropometry and Occlusion: A Cross-Sectional Insight into Finger Measurements and Vertical Dimension of Occlusion in Madhya Pradesh

Journal of Pharmacy and Bioallied Sciences
Introduction: Anthropometry plays a crucial role in forensics and clinical medicine. This study examines the relationship between the vertical dimension of occlusion (OVD) and finger measurements in the Madhya Pradesh population, with a focus on gender ...
Megha Patil, Mukesh Soni, Alka Gupta, Harsh Chansoria, Harshita Sachdev, P Suthakar   +5 more
doaj   +1 more source

Religious 'speculation': the rise of Ifa cults and consumption in post-Soviet Cuba [PDF]

, 2004
With an ethnographic focus on the prestigious cult of Ifá, this article seeks to account for the recent effervescence of Afro-Cuban cult worship in urban Cuba.
Holbraad, M
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Evolutionary thinking among biology students in a third world country

Evolution: Education and Outreach, 2017
Background Evolutionary thinking is traditionally directly related to education and inversely to religiosity. Accordingly, biology students are naturally expected to be more prone to naturalist evolution due to their close contact with this theory and ...
João C. F. Cardoso, Uiara C. Rezende
doaj   +1 more source