Results 61 to 70 of about 130,885 (293)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The lectionary: toward a more balanced selection of texts [PDF]
, 1992 Stories of ...
Schlueter, Carol J.
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The Common-Core/Diversity Dilemma: Revisions of Humean thought, New Empirical Research, and the Limits of Rational Religious Belief [PDF]
, 2015 This paper is the product of an interdisciplinary, interreligious dialogue aiming to outline some of the possibilities and rational limits of supernatural religious belief, in the light of a critique of David Hume’s familiar sceptical arguments ...
Millican, Peter +1 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Revista Cubana de Estomatología, 2012 La belleza y la armonía facial desempeñan una función decisiva en las relaciones sociales del hombre. La afectación estética es el principal motivo de consulta de los pacientes de Ortodoncia.
Yaima Lazo Amador +3 more
doaj
The Paradoxical Beauty of the Cross: Theological Aesthetics and the Doctrine of the Atonement in Athanasius’ Contra Gentes-De Incarnatio [PDF]
, 2011 In his two-part treatise Contra Gentes-De Incarnatio, Athanasius offers an interesting apologetic for the Christian doctrine of the atonement by employing various aesthetic themes and forms of expression drawn from the classical notion of beauty found ...
Little, Marcus
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Critical Analysis of the Misgivings of the Book “A Critical Review of the Theoretical Fundamentals of Prophecy” on the Language of the Quran [PDF]
آموزههای قرآنیIn recent years, some dissident authors, including the author of A Critical Review of the Theoretical Fundamentals of Prophecy have presented critical questions and new misgivings about the topics of the language of the Holy Quran by radical and ...
Hamid Qorbanpour Lafmejani +1 more
doaj +1 more source