Results 81 to 90 of about 130,885 (293)
Los pacientes acuden cada vez con más frecuencia a los servicios estomatológicos en busca de mejorar su aspecto estético. Uno de los métodos más polémicos para el examen de la estética lo constituyen aquellos que se basan en el empleo de la proporción ...
Adriana Lorenzo Uribazo +4 more
doaj
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Los pacientes acuden cada vez con más frecuencia a los Servicios Estomatológicos en busca de mejorar su aspecto estético. Uno de los métodos más polémicos para el examen de la estética lo constituyen aquellos que se basan en el empleo de la proporción ...
Adriana M Lorenzo Uribazo +4 more
doaj
Evil as Privation and Leibniz's Rejection of Empty Space [PDF]
I argue that Leibniz's treatment of void or empty space in the appendix to his fourth letter to Clarke conflicts with the way he elsewhere treats (metaphysical) evil, insofar as he allows that God has created a world with the one kind of privation (evil),
Puryear, Stephen
core
Writ(h)ing Images: Imagination, the Human Form, and the Divine in William Blake, Salman Rushdie, and Simon Louvish [PDF]
In this paper, we address issues in segmentation Of remotely sensed LIDAR (LIght Detection And Ranging) data. The LIDAR data, which were captured by airborne laser scanner, contain 2.5 dimensional (2.5D) terrain surface height information, e.g.
Axel Stähler +16 more
core +1 more source
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
« Nus » ou « vêtus » ? Les dieux avec ou sans épithètes
The MAP project studied the epithets lato sensu attributed to Greek and Semitic gods in inscriptions between 1000 BCE and 400 CE. However, However, the gods are not always mentioned with an epithet when people address them. Can we quantify the proportion
Corinne Bonnet
doaj +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source

