Results 31 to 40 of about 907 (238)
Aquinas on Providence, Control, and Divine Simplicity
TheoLogicaIn this article, I address Joe Schmid’s argument of providential collapse against divine simplicity. After presenting my reservations about Daniel Shield’s solution based on Aquinas’s theory of relations, I outline a three-step strategy to defend ...
Agustín Echavarría
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Religions, 2022 The article presents problems that the concepts of God’s immutability, impassibility, and simplicity pose for Christian theism. Through the critical analysis, the author indicates the roots of these ideas (mostly, but not only, in ancient Greek ...
Marek Słomka
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada +6 more
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Divine Simplicity and the Theory of Action
TheoLogicaThe modal collapse argument states that the traditional doctrine of divine simplicity entails that God necessarily creates whatever he creates and also that all creatures necessarily perform whatever actions they perform. In response to these objections,
Clemente Huneeus
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
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Explaining the Effects of Essence Simplicity and the Gradation of Existence on the Quality of God’s Attributes, from the MullaSadra’s Point of View [PDF]
حکمت معاصر, 2015 Self-existent in its essence has multiple inherent and real qualities. On the other hand, self-existent has the most simple and pure essentiality. The summation of the extreme simplicity and the diversity of God’s qualities is done based on the Mulla ...
Mohammad Hosein Vafaiyan +1 more
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