Results 41 to 50 of about 907 (238)

Simple is as simple does: Plantinga and Ghazālī on divine simplicity

, 2022
This study considers the notion of divine simplicity, the idea that God is not a composite of more basic features, and the criticisms by al-Ghazālī (d. 1111) and Alvin Plantinga of that doctrine.
McGinnis, Jon
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Holy Triune Love

TheoLogica
In this paper, I formulate an alternative to the classical doctrine of divine simplicity. Simply stated, God’s nature is best understood as Holy Triune Love (HTL), and all attributes are best understood as aspects of HTL.
Sean Luke
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

The Antinomic Method of Gregory Palamas: Between Transcendence and Immanence, God’s Essence and Energy, Single and Multiple Trinity

Verbum Vitae, 2023
The article examines the theological method of antinomy and the conceptual solution to the problem of the ontological “gap” between transcendence and immanence of the Holy Trinity in the theological thought of the outstanding Byzantine theologian of the
Viktor Zhukovskyy
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

The Semantics of Divine Attributes according to Avicenna and Its Relevance with the Issue of Language of Religion [PDF]

Comparative Theology, 2014
One of the longstanding questions in philosophy and theology is how to understand and analyze the meanings of attributes which are shared by God and human beings; whether these attributes are predicated to God in ordinary human sense or they have an ...
Fatemeh Suleymani
doaj   +2 more sources

The Specificity of Names Predicated of the Nature of God Based on the Cognition of Created Beings According to St. Thomas Aquinas [PDF]

Studia Gilsoniana
In his reflections on the nature of God, St. Thomas Aquinas maintains that although the divine being, as it exists in itself, is unknowable, it can nevertheless be characterized per analogiam through the perfections proper to creatures.
Paulina Sulenta
doaj   +1 more source