Results 281 to 290 of about 3,239,262 (362)

Correction: Garmaa et al. A Systematic Review and Meta-Analysis of microRNA Profiling Studies in Chronic Kidney Diseases. <i>Non-Coding RNA</i> 2024, <i>10</i>, 30. [PDF]

open access: yesNoncoding RNA
Garmaa G   +10 more
europepmc   +1 more source

3D Membrane Microstructures for Increased Efficiency in Blood‐Gas Transfer

open access: yesAdvanced Science, EarlyView.
Oxygenators for extracorporeal membrane oxygenation are based on hollow fiber membranes. They are associated with many complications, such as thrombosis or systemic inflammation during the therapy. By implementing 3D membrane microstructures for oxygenators, the transfer efficiency of oxygen and carbon dioxide is improved, which can lead to ...
Kai P. Barbian   +9 more
wiley   +1 more source

Quantifying the Single‐Cell Morphological Landscape of Cellular Transdifferentiation through Force Field Reconstruction

open access: yesAdvanced Science, EarlyView.
This study reconstructs the driving force field of fibroblast‐to‐neuron transdifferentiation from sparse single‐cell images by decomposing it into flux and time‐dependent potential gradient, extending the landscape‐flux framework to non‐steady‐state systems.
Chudan Yu   +3 more
wiley   +1 more source

Nature-inspired metaheuristics for optimizing dose-finding and computationally challenging clinical trial designs. [PDF]

open access: yesClin Trials
Wong WK   +7 more
europepmc   +1 more source

Flash Photodynamic Therapy – How the Saturation of Photosensitizer Absorption Enables Selective and Deeper Tumor Treatments

open access: yesAdvanced Science, EarlyView.
FLASH‐PDT uses strongly‐absorbing photosensitizers and pulsed lasers to saturate the photosensitizer absorption at ≈1‐cm tissue depths. This allows for the generation of [ROS] above the necrosis threshold level for tumors, while maintaining [ROS] in peritumoral tissues below that threshold, even when the tumor‐to‐peritumoral tissue ratio is as low as 2.
Luis G. Arnaut   +3 more
wiley   +1 more source

MUC15 Ectodomain Architecture Regulates Integrin Clustering to Control Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
This study uncovers a size‐dependent adhesion paradigm, demonstrating that the glycocalyx protein MUC15 suppresses pancreatic cancer progression by attenuating integrin activation, focal adhesion assembly, and YAP mechanotransduction. Integrating computational modeling and experimental validation, the work reveals a mechanical mechanism by which MUC15 ...
Simei Zhang   +18 more
wiley   +1 more source

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