Results 61 to 70 of about 137,353 (312)

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Execute Justice and Charity for Your People: Jewish Divorce Mediation as a Model for Intrareligious Peacekeeping

open access: yesReligions
This article explores the complex issue of disharmony within religious marriages, focusing on Jewish approaches to divorce. Contrasting Jewish divorce mediation with other religions’ approaches to marital conflict, this article examines two Judaic models:
Sarah M. Nissel
doaj   +1 more source

Post-divorce coaching: a new intervention to facilitate divorce adjustment [PDF]

open access: yesروانشناسی و روانپزشکی شناخت, 2020
Introduction: Family has been the most fundamental social institution underlying societies and human history. Divorce is one of the social issues, which often causes problems for family members and make them vulnerable.
Pendar Fazel   +2 more
doaj  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Marriage Dispute Resolution in Muslim Populated Countries: A Comparative Study of Divorce Law in Indonesia and Singapore

open access: yesLegitima: Jurnal Hukum Keluarga Islam
Purpose – The issue of reasons for divorce is an interesting discussion to study. In Indonesia, the reason for divorce that is mostly submitted by parties who want to divorce is the dispute between husband and wife. The reason for divorce in Law No.
Mohammad Ainul Hakim Hakim
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Marriage, Divorce and Interstate Risk Sharing [PDF]

open access: yes
In this paper we study the importance of marriage for interstate risk sharing. We find that US states in which married couples account for a higher share of the population are less exposed to state-specific output shocks.
Halla, Martin, Scharler, Johann
core   +4 more sources

Cerai Talak di Kota Palopo (Faktor Penyebab dan Solusinga dalam Studi Kasus di Pengadilan Agama)

open access: yesPalita: Journal of Social - Religion Research, 2016
Marriage is one of the manifestations of human nature in the world to find happines, and make their descendant. Unfortunately, not all marriages are lasting until the end of the age, and not a litle ended in divorce.
Muhammad Tahmid Nur
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

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