Results 61 to 70 of about 98,283 (310)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Divorce decisions, divorce laws and social norms [PDF]
This article focuses on the three way relationship between change in divorce law, evolution of divorce rate and evolution of the cultural acceptance of divorce. We consider a heterogeneous population in which individuals differ in terms of the subjective
Magali Recoules, Victor Hiller
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The effect of divorce laws on divorce rates in Europe [PDF]
This paper analyzes a panel of 18 European countries spanning from 1950 to 2003 to examine the extent to which the legal reforms leading to “easier divorce” that took place during the second half of the 20th century have contributed to the increase in ...
Tarja K. Viitanen +1 more
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Cerai Talak di Kota Palopo (Faktor Penyebab dan Solusinga dalam Studi Kasus di Pengadilan Agama)
Palita: Journal of Social - Religion Research, 2016 Marriage is one of the manifestations of human nature in the world to find happines, and make their descendant. Unfortunately, not all marriages are lasting until the end of the age, and not a litle ended in divorce.
Muhammad Tahmid Nur
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Did Unilateral Divorce Laws Raise Divorce Rates? A Reconciliation and New Results [PDF]
Application of the Coase Theorem to marital bargaining suggests that shifting from a consent divorce regime to no-fault unilateral divorce laws should not affect divorce rates. Each iteration of the empirical literature examining the evolution of divorce
Justin Wolfers
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Did Unilateral Divorce Laws Raise Divorce Rates? A Reconciliation and New Results: Comment [PDF]
The seminal papers by Friedberg (1998) and Wolfers (2006) find a positive effect of the regulatory change in divorce laws on divorce rates. Their results are based on analytical weights to correct for heteroskedasticity (WLS).
Ryan C.R. van Lamoen, Martijn I. Dröes
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Exploring the causes of divorce among applicants and experts in the field of divorce in the city of Rasht: emphasizing the commission of crimes arising from marital maladjustment [PDF]
مجله علوم روانشناختیBackground: Divorce is a social issue that has witnessed an upward trend in recent years, exerting negative effects on families, children, and society. One significant factor contributing to divorce is marital misconduct, which may lead to the commission
Hojjat Falah Khajakini +3 more
doaj