LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Cerai Talak di Kota Palopo (Faktor Penyebab dan Solusinga dalam Studi Kasus di Pengadilan Agama)
Marriage is one of the manifestations of human nature in the world to find happines, and make their descendant. Unfortunately, not all marriages are lasting until the end of the age, and not a litle ended in divorce.
Muhammad Tahmid Nur
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Exploring the causes of divorce among applicants and experts in the field of divorce in the city of Rasht: emphasizing the commission of crimes arising from marital maladjustment [PDF]
Background: Divorce is a social issue that has witnessed an upward trend in recent years, exerting negative effects on families, children, and society. One significant factor contributing to divorce is marital misconduct, which may lead to the commission
Hojjat Falah Khajakini +3 more
doaj
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Relationship between Divorce and Well-being among Older Europeans
This study explores the relationship between divorce and well-being among older Europeans (50+), utilizing data from eight waves of the Survey on Health, Ageing and Retirement in Europe (SHARE).
Giedrius Rupšys +2 more
doaj +3 more sources
The effect of divorce laws on divorce rates in Europe [PDF]
This paper analyzes a panel of 18 European countries spanning from 1950 to 2003 to examine the extent to which the legal reforms leading to “easier divorce” that took place during the second half of the 20th century have contributed to the increase in ...
Libertad González Luna +1 more
core
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
The Effects of Near and Actual Parental Divorce on Student Achievement and Misbehavior [PDF]
It is well-documented that children whose parents divorced experience worse outcomes than children from two-parent families. However, data and methodological limitations have made it difficult to know whether declines were evident prior to the divorce or
Mark L. Hoekstra
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source

