Results 71 to 80 of about 73,673 (310)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

The Durability of Marriage in Poland in the Years 1945–1950 in the Light of the Practice of the District Court in Kraków and in Słupsk

Krakowskie Studia z Historii Państwa i Prawa
The new law on marriage (and civil status records) introduced in post-war Poland on 1 January 1946 created a new legal status for many planning to enter into marriage and those who wanted to divorce ...
Zdzisław Zarzycki, Paweł Kaźmierski
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Predicting divorce in non-divorced and divorce applicant couples based on early maladaptive schemas, communication skills and communication patterns

مجله علوم روانشناختی, 2022
Background: Communication skills, communication patterns, and maladaptive schemas are all key predictors of divorce, and each has been examined separately in numerous studies.
zahra manouchehrabadi, mohammad dadgaran, ali delavar   +2 more
doaj  

Divorce and Death in the Family Firm – A Business Law Perspective [PDF]

, 2010
Kajsa Haag, Lars-Göran Sund, Hanna Almlöf   +2 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

‘Take the Money and Run’: Dutch Evidence on Inheritance and Transfer Receiving and Divorce [PDF]

, 2021
Stefania Basiglio
openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

ENSURING THE BEST INTERESTS OF THE CHILD IN PARENTS` CONFLICT: EXPERIENCES OF DIVORCING FAMILIES

, 2022
Brigita Kairienė, Gražina Čiuladienė, Agata Balionis   +2 more
openalex   +2 more sources