Results 81 to 90 of about 73,673 (310)

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

A qualitative assessment of strategies affecting adaptability in the post-divorce adaptation process: knowledge based on the experience of divorced women

مجله علوم روانشناختی, 2021
Background: For many women, divorce means coping with extreme stress and emotional instability. To meet the challenges after divorce, divorced women need to be more resilient using different strategies.
farahnaz jeloyari, somayeh kazemian, Ebrahim Naeimi, Abdolah Motamedi   +3 more
doaj  

The effectiveness of acceptance and commitment- group therapy on perceived stress and Marital Distress in women with major depressive disorder seeking divorce

, 2023
Saeed Imani, Morteza Zakeri, Amirhoseyn Bahadivand   +2 more
openalex   +2 more sources

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Development of A Causal Model of Post-Divorce Adjustment Based on Social and Psychological Factors in Divorced Women in Shiraz, Iran

Armaghane Danesh Bimonthly Journal, 2022
Background & aim: Divorce brings emotional separation and psychological pressures for most women, which requires the most changes for re-adaptation in these people.
L Mohandes, H Javidi, M Barzegar, N Sohrabi   +3 more
doaj  

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Forgiveness, gratitude, and the flourishing of emerging adults with divorced parents

, 2022
Nastasya Ryoko Bonang Tessy, Setiasih Setiasih, Nanik Nanik   +2 more
openalex   +2 more sources

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Development of the Prescriptive Beliefs Regarding Divorce Scale: Validity and Reliability Study

, 2020
Ayşegül SAYAN KARAHAN, İ̇brahim YILDIRIM   +1 more
openalex   +2 more sources

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source