Results 101 to 110 of about 195,313 (255)

An Approach to Dizziness [PDF]

, 1976
Dizziness is a vague and ubiquitous symptom which frequently frustrates and perplexes the clinician. Dizziness in the broad sense implies any unpleasant sensation of disturbed relationship to surrounding objects.
Grindal, Alan B.
core  

CYP3A5 genetic variability influences sildenafil and metabolite in pulmonary hypertension

British Journal of Clinical Pharmacology, EarlyView.
Aim Interindividual variability in sildenafil response among pulmonary hypertension patients (PH) may be influenced by CYP3A5 polymorphisms. CYP3A5*3 allele reduces CYP3A5 activity and affects sildenafil metabolism. This study investigated the associations between CYP3A5 genotype and plasma concentrations of sildenafil and N‐desmethyl sildenafil, as ...
Pranisa Wongwien, Burabha Pussadhamma, Sirimas Kanjanawart, Thikhumporn Areesinpitak, Nontaya Nakkam, Chingching Foocharoen, Wichittra Tassaneeyakul, Suda Vannaprasaht   +7 more
wiley   +1 more source

The Sense of Dizziness in Deaf-Mutes

, 1882
THE SENSE OF DIZZINESS IN DEAF-MUTES The Sense of Dizziness in Deaf-Mutes (4) (-
James, W.
core   +1 more source

Advances in pathogenesis, novel therapeutic strategies and interventions for age-related hearing loss

Frontiers in Molecular Neuroscience
Age-related hearing loss (ARHL), or presbycusis, represents one of the most prevalent sensory dysfunctions in the elderly people. It is characterized by progressive hearing deterioration that significantly impairs quality of life and increases the risk ...
Zhiyang Wen, Zhiyang Wen, Yinfei Liang, Yinfei Liang, Dongxue Wu, Dongxue Wu, Huiqing Wu, Huiqing Wu, Zhicheng Li, Zhicheng Li, Gendi Yin, Gendi Yin, Xiangli Zeng, Xiangli Zeng   +13 more
doaj   +1 more source

A scoping review of adverse events associated with concomitant beta‐adrenoreceptor blockers and selective serotonin reuptake inhibitors

British Journal of Clinical Pharmacology, EarlyView.
Beta‐adrenoreceptor blockers (beta‐blockers) and selective serotonin reuptake inhibitors (SSRIs) are commonly used medications and often used together, such as for the treatment of anxiety. However, there is no recent review of any potential adverse events related to concomitant use of medicines from each group.
Ziyi Cai, James Sutton, Charlotte Archer, Caroline S. Copeland, Joseph Hayes, Charles E. Leonard, Nicky Lidbetter, Kenneth K. C. Man, Faraz Mughal, Ian C. K. Wong, Hayley C. Gorton   +10 more
wiley   +1 more source

The social impact of dizziness in London and Siena

, 2009
Although dizziness is a common presenting symptom in general and hospital practice, its social cost is not known. We assessed the social and work life impact of dizziness on patients in two contrasting European cities, Siena and London.
Bronstein, A.M., GOLDING JF, GRESTY MA, Silove, Y., SILOVE Y., Gresty, M.A., Mandalà, M., Shetye, A., BRONSTEIN AM, SHETYE A, Nuti, D., MANDALA', MARCO, NUTI, DANIELE, Golding, J.F., Anu Shetye, Daniele Nuti, Adolfo M. Bronstein, John F. Golding, Michael A. Gresty, Marco Mandalà, Yvonne Silove   +20 more
core   +1 more source

Systematic review of clinical trials and cohort studies evaluating HIV post‐exposure prophylaxis (PEP) regimens to inform updated Canadian guidelines

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background We conducted a systematic review of clinical trials and cohort studies on HIV post‐exposure prophylaxis (PEP) regimens to inform updated 2025 Canadian guidelines. Methods We searched Medline and Embase (July 2017–June 2024) for studies reporting on: HIV acquisition, PEP completion, adverse events (AEs) leading to discontinuation and/
Stanley O. Onyegbule, Maryam Habib, Rija Khalid, Jessie Tu, Deborah Yoong, Jaris Swidrovich, Wale Ajiboye, Patrick O'Byrne, Ameeta E. Singh, Jean‐Guy Baril, Tatiana Sotindjo, Mark W. Hull, Darrell H. S. Tan   +12 more
wiley   +1 more source

Dizziness in vestibular schwannomas

Dizziness associated with vestibular schwannomas can be considered a diagnostic feature, a posttreatment challenge, or an issue in patients undergoing a wait-and-scan approach.
Tjernström, Fredrik, Magnusson, Måns, Kullar, Peter, Kullar, Peter,, Magnusson, Måns,, Lund University., Tjernström, Fredrik,   +6 more
core   +1 more source

Pharmacokinetic and pharmacodynamic interaction of enavogliflozin, a sodium‐glucose cotransporter 2 inhibitor, with glimepiride and metformin in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims Enavogliflozin, a sodium‐glucose cotransporter 2 inhibitor, is expected to be coadministered with antihyperglycaemic drugs with different mechanisms of action. This study aimed to investigate the pharmacokinetic (PK) and pharmacodynamic (PD) interactions between enavogliflozin, glimepiride and metformin.
Kyungrin Chang, Yoonjin Kim, Daye Jung, Jae Min Cho, Joo‐Youn Cho, SeungHwan Lee   +5 more
wiley   +1 more source

Chiari I Malformation: Review and Update of Current Treatment Options

Clinical Anatomy, EarlyView.
ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo, Shuhei Shiino, Stephen Z. Shapiro, Brianna L. Hines, Noritaka Komune, Carmine Antonio Donofrio, Filippo Badaloni, Antonio Fioravanti, Joseph Lockwood, C. J. Bui, Aaron S. Dumont, R. Shane Tubbs   +11 more
wiley   +1 more source