Results 111 to 120 of about 300,947 (286)

A Case Report of Using Korean Medicine for the Treatment of Anemia of Chronic Disease (ACD) in a Patient with Dizziness, Anorexia, and General Weakness [PDF]

, 2021
Dong-Won Kim, Bong-hun Kil, Hye-mi Jo, Da-hae Jung, Hye-soo Youn, Eun-chang Lee, Jee-yeong Won, Jung Eun Lee   +7 more
openalex   +1 more source

Safety and pharmacokinetics of a novel potent GABA analogue crisugabalin in Chinese subjects with various degrees of renal impairment

British Journal of Clinical Pharmacology, EarlyView.
Aims Crisugabalin is a novel calcium channel α2δ subunit ligand and a highly selective oral gamma‐aminobutyric acid (GABA) analogue developed for the treatment of diabetic peripheral neuropathic pain (DPNP) and postherpetic neuralgia (PHN). This study investigated pharmacokinetic properties and safety of crisugabalin in subjects with renal impairment ...
Shibeilei Lin, Ye Wang, Chao Hu, Yanhuan Feng, Xi Tang, Ping Fu, Jia Miao   +6 more
wiley   +1 more source

Cognitive conflict and restructuring: The neural basis of two core components of insight

AIMS Neuroscience, 2019
Sometimes, the solution to a difficult problem simply pops into mind. Such a moment of sudden comprehension is known as “insight”. This fundamental cognitive process is crucial for problem solving, creativity and innovation, yet its true nature remains ...
Amory H. Danek, Virginia L. Flanagin
doaj   +1 more source

Specific immunotherapy in Albanian patients with anaphylaxis to hymenoptera venoms [PDF]

, 2002
Background: Severe allergic reactions during rush-specific immunotherapy (Rush-SIT) may occur in the treatment of hymenoptera sting allergy. The objective of the present study was to examine the characteristics of allergic reactions during Rush-SIT in a ...
Dinh, Q. Thai, Fischer, Axel, Groneberg, Jan David Alexander, Mingomataj, Ervin, Peiser, Christian, Priftanji, Alfred, Qirko, Etleva   +6 more
core  

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Relationship between Dual-task Timed Up and Go test and Clinical Outcomes in Patients with Chronic Dizziness/Vertigo

, 2021
Hirofumi Ogihara, Tomohiko Kamo, Ryozo Tanaka, Takumi Kato, Masato Azami, Mayumi Endo, Reiko Tsunoda, Hiroaki Fushiki   +7 more
openalex   +2 more sources

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman, Mathieu Félices, Bhaskar Pandurangavittal, Sanman Ghorpade, Caroline Easterbrook, Marcin Zabielski, Oscar Della Pasqua   +6 more
wiley   +1 more source

A retrospective analysis of two tertiary care dizziness clinics: a multidisciplinary chronic dizziness clinic and an acute dizziness clinic

Journal of Otolaryngology - Head and Neck Surgery, 2019
Background Vertigo remains a diagnostic challenge for primary care, emergency, and specialist physicians. Multidisciplinary clinics are increasingly being employed to diagnose and manage patients with dizziness. We describe, for the first time in Canada,
Phillip Staibano, Daniel Lelli, Darren Tse   +2 more
doaj   +1 more source

Hypnotic doses of fazamorexant induced less impairment on balance and cognition than zolpidem in healthy younger and elderly individualse

British Journal of Clinical Pharmacology, EarlyView.
Aims Fazamorexant is a dual orexin receptor antagonist being developed for the treatment of insomnia. This study aims to determine the dose‐exposure‐response relationship of single‐dose fazamorexant vs. zolpidem in young adult and elderly healthy Chinese volunteers. Methods This single‐centre, randomized, double‐blind, double‐dummy, placebo‐ and active‐
Chen Xia, Huang Xingxing, Jin Lu, Wang Ruwei   +3 more
wiley   +1 more source

Administration of Nebulized Ketamine for Managing Acute Pain in the Emergency Department: A Case Series [PDF]

, 2020
Ketamine administration in sub-dissociative doses in the emergency department (ED) results in effective pain relief in patients with acute traumatic and non-traumatic pain, chronic pain, and opioid-tolerant pain.
Butt, Mahlaqa, Drapkin, Jefferson, Hossain, Rukhsana, Likourezos, Antonios, Masoudi, Aidin, Motov, Sergey   +5 more
core