Results 111 to 120 of about 99,199 (313)

Tafasitamab as Monotherapy or in Combination in Japanese Patients With B‐Cell Non‐Hodgkin Lymphoma: Results From the Phase 1b J‐MIND Study

Cancer Science, EarlyView.
J‐MIND evaluated the safety and tolerability of tafasitamab, a CD19‐targeting monoclonal antibody, alone or in combination with other therapies in Japanese patients with B‐cell non‐Hodgkin lymphoma (NHL). Most common treatment‐emergent adverse events across all groups were hematological, and no serious tafasitamab treatment‐related or fatal adverse ...
Koji Izutsu, Noriko Fukuhara, Junichiro Yuda, Youko Suehiro, Shigeru Kusumoto, Marie‐Laure Casadebaig, Kazumi Suzukawa, Kentaro Fukushima   +7 more
wiley   +1 more source

Phase 1/2 Study of Crizotinib in Children With Relapsed/Refractory ALK‐Positive Anaplastic Large Cell Lymphoma or Neuroblastoma in Japan

Cancer Science, EarlyView.
The safety and antitumor activity of crizotinib at a dose of 165 mg/m2 BID were evaluated in 16 patients with ALK‐positive ALCL in Japan. The most common grade 3 or 4 adverse event was neutropenia. The steady‐state Cmax and AUCtau of crizotinib at 165 mg/m2 BID were higher than expected. The objective response rate was 72.7% (90% CI, 43.6%–92.1%) among
Tetsuya Mori, Akiko Kada, Tomoo Osumi, Daisuke Tomizawa, Yuhki Koga, Reiji Fukano, Kengo Takeuchi, Ukihide Tateishi, Osamu Miyazaki, Ryuta Asada, Akiko M. Saito, Kei Fukuhara, Masahiro Sekimizu   +12 more
wiley   +1 more source

Danlou tablet alleviates sepsis-induced acute lung and kidney injury by inhibiting the PARP1/HMGB1 pathway

Heliyon
Background: Sepsis-associated acute lung injury (ALI) and acute kidney injury (AKI) are common complications that significantly impact patient prognosis.
Yongjing Yu, Zhixi Li, Chang Liu, Yue Bu, Weidong Gong, Juan Luo, Ziyong Yue   +6 more
doaj   +1 more source

Selection of an appropriate left-sided double-lumen tube size for one-lung ventilation among Asians

Annals of Cardiac Anaesthesia, 2017
Context: Selecting an appropriate size double-lumen tube (DLT) for one-lung ventilation has always been a challenge as most choose it based on experience or using the existing guidelines based on gender and height.
Siti Salwani Ideris, Muhamad Rahimi Che Hassan, Mohd Ramzisham Abdul Rahman, Joanna Su Min Ooi   +3 more
doaj   +1 more source

Governance in Systems Based on Distributed Ledger Technology (DLT): A Comparative Study

, 2021
Ellen Naudts, Timothy Aerts, leonard franken, Aimo Pieterse   +3 more
openalex   +1 more source

Can Central Bank Digital Currencies Promote the Internationalization of Currencies?

European Financial Management, EarlyView.
ABSTRACT Using multinational data (2000–2023), this study employed system GMM and fixed‐effects models to examine CBDC's impact on currency internationalization through a framework measuring ‘market acceptance’ and ‘policy drive.’ The results indicated that CBDC advancement significantly promotes currency internationalization.
Haodong Gu
wiley   +1 more source

Subglottic Stenosis After Double‐Lumen Tube Intubation With Reintubation: A Case Report and Review of Japanese Cases

Clinical Case Reports
Subglottic stenosis after double‐lumen tube (DLT) intubation is more likely to occur when an oversized DLT, specifically a 35 Fr DLT, is used in older, shorter women. Reintubation in such cases is challenging and may cause additional traumatic laryngitis.
Masami Suzuki, Naohiro Yoshida
doaj   +1 more source

Coalition Formation for Sustainable Blockchain Governance: Insights From the Hedera Case

Information Systems Journal, EarlyView.
ABSTRACT Sustainable governance is essential for blockchain networks to achieve widespread adoption and deliver long‐term business value. Prior blockchain initiatives indicate that inadequate governance structures often lead to limited adoption or eventual project failure, underscoring the importance of decentralised governance for building resilient ...
Christophe Viguerie, Horst Treiblmaier
wiley   +1 more source

Effect of a 3D-printed reconstruction automated matching system for selecting the size of a left double-lumen tube: a study protocol for a prospective randomised controlled trial

BMJ Open
Introduction Lung isolation is primarily accomplished using a double-lumen tube (DLT) or bronchial blocker. A precise and accurate size of the DLT is a prerequisite for ensuring its accurate placement. Three-dimensional (3D) reconstruction technology can
Yi Xu, Huaiming Wang, Fei Wang, Hongwei Zhang, Hong Yu, Lantao Li, Yihao Zhu, Feng Yin, Fei Fei, Wusong Liu, Bowen Duan, Ying Jia   +11 more
doaj   +1 more source

Revisiting the relationship between stomatal size and speed across species – a meta‐analysis

New Phytologist, EarlyView.
Summary The rate of stomatal opening and closure in response to changes in light affects leaf photosynthesis and water use. However, it is unclear how strongly stomatal size (SS) and density (SD) influence stomatal conductance (gs) kinetics, and whether variation arises from methodological differences, guard cell type or degree of amphistomaty.
Nik Woning, Yazen Al‐Salman, Elias Kaiser, Sarah R. Berman, Oliver Brendel, Francisco Javier Cano, Sebastien Carpentier, Mauro Centritto, Paul L. Drake, Maxime Durand, David Eyland, Peter J. Franks, Theo Gerardin, Oula Ghannoum, Matthew Haworth, Liisa Kübarsepp, Tracy Lawson, Didier Le Thiec, Yong Li, Leo F. M. Marcelis, Giovanni Marino, Lorna McAusland, Christopher D. Muir, Ülo Niinemets, Tiago D. G. Nunes, Michael T. Raissig, Kazuma Sakoda, Daisuke Sugiura, Tiina Tosens, Qiangqiang Zhang, Ningyi Zhang, Silvere Vialet‐Chabrand   +31 more
wiley   +1 more source