Results 71 to 80 of about 55,611 (129)
Cell Proliferation, EarlyView.Lung cancer development involves mechanisms like reduced EGFR/EGF ubiquitination driving cancer cell behaviors and immune evasion via loss of PD‐1/PD‐L1 ubiquitination. Balancing ubiquitination and deubiquitination may be a potential therapeutic strategy. ABSTRACT Non‐small cell lung cancer (NSCLC) remains a leading cause of cancer mortality.
Guangyao Zhou +5 more
wiley +1 more source
European Journal of Haematology, Volume 114, Issue 6, Page 938-952, June 2025.ABSTRACT The treatment landscape for relapsed or refractory acute lymphoblastic leukemia (RR ALL) has evolved significantly with the introduction of monoclonal antibodies such as blinatumomab and inotuzumab ozogamicin. These agents have demonstrated remarkable efficacy, achieving high response rates and minimal residual disease (MRD) negativity ...
Antonella Bruzzese +11 more
wiley +1 more source
Dual complex of log Fano pairs and its application to Witt vector cohomology
, 2019 We prove the contractibility of the dual complexes of weak log Fano pairs. As applications, we obtain a vanishing theorem of Witt vector cohomology of Ambro-Fujino type and a rational point formula in dimension three.Comment: 25 ...
Nakamura, Yusuke
core
European Journal of Haematology, EarlyView.ABSTRACT The treatment of elderly, nonfit acute myeloid leukemia (AML)/MDS patients with relapsed/refractory (R/R) disease remains challenging. As histone demethylase LSD1 (KDM1A) is a rational therapeutic target in AML, we conducted a phase I trial (“rolling‐six design”) with the LSD1 inhibitor tranylcypromine (TCP, dose levels [DL] 20, 40, 60, 80 mg ...
Michael Kruszewski +22 more
wiley +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Acquired equine polyneuropathy in Nordic horses (AEP) is the most prevalent equine polyneuropathy in Norway, Sweden, and Finland and is characterised by pelvic limb knuckling due to metatarsophalangeal extension dysfunction.
Anna May +6 more
wiley +1 more source
Are Non‐Audit Services Economically Beneficial to Audit Clients?
International Journal of Auditing, EarlyView.ABSTRACT We study the association between non‐audit services (NAS) and the potential economic benefit to audit clients of higher investment efficiency. Little prior research has examined whether NAS produces measurable benefits or simply additional costs for clients procuring them.
Marshall A. Geiger +3 more
wiley +1 more source
Phase I study of pomalidomide in relapsed or refractory Waldenström macroglobulinaemia
British Journal of Haematology, EarlyView.
Karan L. Chohan +9 more
wiley +1 more source
Journal of Animal Breeding and Genetics, EarlyView.ABSTRACT In this study, we aimed to evaluate the genetic association between fertility traits, milk yield and the fat: protein ratio (FPR) on the test day in primiparous Holstein cows. The analysed traits were milk yield (TDMY) and FPR assessed on the test day, as well as the following fertility traits: period from calving to first service (CFS), days ...
Amauri Felipe Evangelista +5 more
wiley +1 more source
Journal of Oral Rehabilitation, EarlyView.ABSTRACT Background Behavioural cognitive factors, like kinesiophobia and coping skills like hypervigilance, may contribute to a worse prognosis of TMD symptoms. However, there is a lack of evidence about the prevalence and relationship of hypervigilance and kinesiophobia with TMD. Objective This study aimed to assess the prevalence and associations of
Pedro Miguel Teixeira Carvas Cebola +8 more
wiley +1 more source
Application of the DLT method to anthropometry.
Journal of the Anthropological Society of Nippon, 1991 The direct linear transformation (DLT) method was applied as a tool in the field of anthropometry. Using four video cameras which are arranged surrounding the subjects, we attempted to detect the reference points in the trunk of body and produce three dimensional coordinates of the points by the DLT method.
openaire +3 more sources