Results 121 to 130 of about 167,380 (289)

Google Adtech – Break Up or Break Out?

Utrecht Law Review
The European Commission recently proposed a break up of Google’s display advertising business. We argue that the market definition used by the Commission risks being too narrow and propose expanding it to include Google’s broader ecosystem. We then ask a
Todd Davies, Zlatina Georgieva
doaj   +1 more source

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

Advanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason, Anindya Sen, Suhan Cho, Se Jong Lee, Keyata Thompson, Md Musavvir Mahmud, Poornima Dubey, Talia Guardia, Anthony Kim, Stuart Martin, Nathan Wright, Konstantinos Konstantopoulos, Aikaterini Kontrogianni‐Konstantopoulos   +12 more
wiley   +1 more source

Tensile properties and dynamic mechanical analysis of kenaf/epoxy composites Authors

Journal of Mechanical Engineering and Sciences
Kenaf fibre-reinforced polymer composites could offer low-cost, biodegradable, recyclable, and renewable materials. The hydrophilic kenaf fibres exhibit poor compatibility with the hydrophobic epoxy matrix as compared to their synthetic counterparts and ...
A. H. Abdullah , I. Tharazi , F. M. Salleh, N. H. A. Halim , Z. H. Solihin, A. P. Marzuki , K. Abdan   +6 more
doaj   +1 more source

3D Large‐Scale Subwavelength‐Resolution Sound Sheet Tomography Based on an Active and Programmable Circular Meta‐Array

Advanced Science, EarlyView.
A programmable 2048‐element circular ultrasound array combined with a compact acoustic lens produces a thin “sound sheet” over a large field of view, and records echoes with wide angular diversity across the ring aperture. Coherence‐enhanced beamforming converts full‐matrix data into high‐contrast tomographic slices, delivering near‐diffraction‐limited
Qiu‐De Zhang, Zi‐Bin Lin, Zhuo Chen, Zhao‐Hui Liu, Jin‐Lian He, Jun‐Jie Song, Long‐Sheng Zeng, Liang Zhou, Ming‐Yue Ding, Yu‐Gui Peng, Ming Yuchi, Xue‐Feng Zhu   +11 more
wiley   +1 more source

Hierarchical Artificial Muscle with Nonlinear Elasticity for Antagonistic and Cyclic Robotics

Advanced Science, EarlyView.
We construct hierarchical muscles by plying nylon fibers around a heating wire. The hierarchical muscle shows a J‐shaped passive curve, which shows benefit in antagonistic muscle pair and work accumulation mechanism. We also develop a computational, first‐principle model to understand the physics of both active actuation stroke and passive J‐curve ...
Samuel Tsai, Liuyang Cheng, Ali Albazroun, Qiong Wang, Jeongmin Kim, Arman Tekinalp, Soonwook Kim, Charlie Simcox, Ryne Downing, Vagish Sivaramakrishnan, Grace Carsello, Miles Bimrose, Wonsik Eom, William P. King, Mattia Gazzola, Sameh Tawfick   +15 more
wiley   +1 more source

DMA processor

, 2001
The DMA (Direct Memory Access) controller, is often a non-programmable hardware. As new peripheral interfaces are introduced there is often a need to change the DMA operation and therefore the design of the DMA controller. Changing the design of the DMA controller is often expensive and time-consuming.
openaire   +1 more source

Nanoscale Covalent Organic Framework Confinement Enables Ultratough and Hyperelastic Hydrogels Applied as High‐Performance Electrolytes

Advanced Science, EarlyView.
Confinement by nanoscale covalent organic frameworks reinforces hydrogels, imparting exceptional mechanical strength and ionic conductivity for high‐performance electrolyte applications. ABSTRACT Hydrogels are widely applied in various fields, including energy storage and flexible electronics. However, their mechanical properties often fail to meet the
Peiyao Yan, Wei Zhao, Hao Wang, Lu Wu, Yedong Ma, Binting Huang, Hantao Xu, Xueyan Liu, Siqi Liu, Xinyu Dong, Xiaoyang Zhang, Wei Zhai, Weiwei Zhang, Lin Xu, Dan Zhao, Chaobin He   +15 more
wiley   +1 more source

Multifunctional Bioactive Scaffold Facilitating BMSCs‐Driven Osteogenesis and Vascularization in Critical‐Sized Bone Defect Repair

Advanced Science, EarlyView.
A dual‐network bFGF@CB‐gel integrates: i) ChSMA scaffold (mechanical support/BMSCs delivery); ii) BC carrier (sustained bFGF release via EGFL/Itga2b and COMP/PI3K/AKT for adhesion/osteogenesis); iii) bFGF/PI3K/AKT/eNOS for angiogenesis. This rational, synergistic design addresses CSD bone regeneration challenges.
Yunze Feng, Bingzhi Chen, Yu Xu, Xin Xu, Bingtao Hu, Tongbo Li, Dingxin Zhang, Baoshuai Bai, Chen Liu, Wanlong Xu, Le Li, Wencan Zhang, Haipeng Si   +12 more
wiley   +1 more source

Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity

Advanced Science, EarlyView.
This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao, Hong‐Yi Zhao, Chengyi Li, Hanning Wen, Fang Ke, Qiuxia Li, Miao He, Bo Wen, Zhongwei Liu, Kai Sun, Wei Gao, Duxin Sun   +11 more
wiley   +1 more source

Dynamic Covalent Networks of Molecular Clusters for Hard and Impact‐Resistant Glass with Feasible Processability

Advanced Science, EarlyView.
Molecular granular material glass is fabricated by crosslinking sub‐nm POSS clusters with dynamic borate ester bonding while the materials combine high transparency, modulus, and hardness with superior impact resistance and (re)processability, offering a promising strategy for creating robust yet highly processable organic glasses.
Haiyan Xiao, Jia‐Fu Yin, Linjie Lan, Wei Liu‐Fu, Panchao Yin   +4 more
wiley   +1 more source