Results 1 to 10 of about 496 (101)

2,6-DMBQ is a novel mTOR inhibitor that reduces gastric cancer growth in vitro and in vivo [PDF]

Journal of Experimental and Clinical Cancer Research, 2020
Background Fermented wheat germ extract has been reported to exert various pharmacological activities, including anti-oxidant, anti-cell growth and cell apoptosis in various cancer cells.
Xiaomeng Xie, Kangdong Liu, Zigang Dong   +2 more
exaly   +8 more sources

2,6-DMBQ suppresses cell proliferation and migration via inhibiting mTOR/AKT and p38 MAPK signaling pathways in NSCLC cells

Journal of Pharmacological Sciences, 2021
2,6-Dimethoxy-1,4-benzoquinone (2,6-DMBQ) is the major bioactive compound found in fermented wheat germ extract. Although fermented wheat germ extract has been reported to show anti-proliferative and anti-metabolic effects in various cancers, the ...
Xiaomeng Xie, Zigang Dong, Dong Joon Kim   +2 more
exaly   +6 more sources

Effects of one haustorium-inducing quinone DMBQ on growth and development of root hemiparasitic plant Monochasma savatieri [PDF]

Ciencia Rural, 2020
: Monochasma savatieri Franch. ex Maxim is a perennial, parasitic herb used in traditional Chinese medicine and its wild resources have decreased sharply in recent years due to destructively harvesting and habitat destruction.
Lanlan Chen, Zaibiao Zhu, Qiaosheng Guo   +2 more
exaly   +7 more sources

A copper-dependent redox-based hydrogen peroxide perception in plants [PDF]

Nature Communications
Redox-related molecules, such as quinones and reactive oxygen species (ROS), are important signaling molecules for all living organisms. A plant-specific leucine-rich repeat receptor-like kinase (LRR-RLK) CANNOT RESPOND TO DMBQ 1 (CARD1), also known as ...
Nobuaki Ishihama, Yohta Fukuda, Yumiko Shirano, Kazuhiro J. Fujimoto, Kaori Takizawa, Ryoko Hiroyama, Hiroki Ito, Mayumi Nishimura, Takeshi Yanai, Tsuyoshi Inoue, Ken Shirasu, Anuphon Laohavisit   +11 more
doaj   +3 more sources

Wheat Germ Fermentation with Saccharomyces cerevisiae and Lactobacillus plantarum: Process Optimization for Enhanced Composition and Antioxidant Properties In Vitro [PDF]

Foods, 2022
Wheat germ, a by-product of the flour milling industry, is currently commercialized mainly for animal feed applications. This study aims to explore and optimize the process of wheat germ fermentation to achieve products with enhanced nutritional ...
Elnaz Bayat, Marzieh Moosavi-Nasab, Mahboubeh Fazaeli, Marjan Majdinasab, Armin Mirzapour-Kouhdasht, Marco Garcia-Vaquero   +5 more
doaj   +3 more sources

Formation of 2,6-DMBQ in anthocyanin-rich foods

LWT - Food Science and Technology, 2020
Abstract The naturally occurring 2,6-dimethoxybenzoquinone (DMBQ) has anti-bacterial, anti-fungal and anti-cancer activities. As it is probably formed in plants via oxidative degradation of the anthocyanin malvidin and its glycosides, a targeted analysis of the DMBQ concentration of different wines and grape juices was performed.
Thorben Detering, Ralf G Berger
exaly   +3 more sources

[Mechanism of 2,6-DMBQ attenuates airway inflammatory responses in asthmatic mice via the mTOR signaling pathway]. [PDF]

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
To investigate the therapeutic effects and mechanisms of 2,6-dimethoxy-1,4-benzoquinone (2,6-DMBQ) in a mouse model of asthma.SPF-grade BALB/c mice were randomly divided into 7 groups (n=8 each group): normal control group, ovalbumin (OVA) group, dimethyl sulfoxide+corn oil group, budesonide (BUD) group, and low, medium, and high dose 2,6-DMBQ groups ...
Juan, Li, Shu-Fang, Li, Xiao-Man, Xiong, Qiu-Yan, Yang, Xue-Li, Xie, Yan-Li, Zhang   +5 more
europepmc   +4 more sources

Production of 2-Methoxy-1,4-benzoquinone (2-MBQ) and 2,6-Dimethoxy-1,4-benzoquinone (2,6-DMBQ) from Wheat Germ Using Lactic Acid Bacteria and Yeast

Food Engineering Progress, 2010
Wheat germ contains the glycosylated forms of 2-methoxy-p-benzoquinone (2-MBQ) and 2,6-dimethoxy-p-benzoquinone (2,6-DMBQ), both of which have antimicrobial and immunostimulatory effects. Conversion of glycosylated 2-MBQ and 2,6-DMBQ to their more functional unglycosylated forms requires enzymatic action of β-glucosidase.
Myoung-Dong Kim, Kim Myoung-Dong
exaly   +3 more sources

Effects of Benzoquinones on Radicles of Orobanche and Phelipanche Species [PDF]

Plants, 2021
The holoparasitic broomrape weeds (Orobanche and Phelipanche species) cause severe yield losses throughout North Africa, the Middle East, and Southern and Eastern Europe. These parasitic weeds form an haustorium at the tip of their radicles to infect the
Mónica Fernández-Aparicio, Marco Masi, Alessio Cimmino, Antonio Evidente   +3 more
doaj   +3 more sources

Reactive Oxygen Species (ROS) Generation Is Indispensable for Haustorium Formation of the Root Parasitic Plant Striga hermonthica

Frontiers in Plant Science, 2019
The parasitic witchweed Striga hermonthica causes devastating damage to crops in sub-Saharan Africa, yet the mechanism of its parasitism is not well understood.
Songkui Cui, Satoko Yoshida
exaly   +4 more sources