Results 21 to 30 of about 130,419 (249)
Orphanet Journal of Rare Diseases, 2012 Duchenne muscular dystrophy (DMD) is a severe, progressive muscle-wasting disorder, while Becker muscular dystrophy (BMD) is milder muscle disease [1]. Both are caused by mutations in dystrophin, a protein, which stabilizes muscle fibers during contraction by linking muscle actin to the extracellular matrix.
Annemieke Aartsma-Rus +4 more
openaire +2 more sources
Dystrophin gene editing by CRISPR/Cas9 system in human skeletal muscle cell line (HSkMC) [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Duchene muscular dystrophy (DMD) is a progressive neuromuscular disease caused by mutations in the DMD gene, resulting in the absence of dystrophin expression leading to membrane fragility and myofibril necrosis in the muscle cells. Because
Mahintaj Dara +5 more
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Dynamic mode decomposition of numerical data in natural circulation
Brazilian Journal of Radiation Sciences, 2021 Dynamic mode decomposition (DMD) has been used for experimental and numerical data analysis in fluid dynamics. Despite of its advantages, the application of the DMD methodology to investigate the natural circulation in nuclear reactors are very scarce in
José Luiz Horacio Faccini
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EXPLORING TRANSIENT, NEUTRONIC, REDUCED-ORDER MODELS USING DMD/POD-GALERKIN AND DATA-DRIVEN DMD [PDF]
EPJ Web of Conferences, 2021 There is growing interest in the development of transient, multiphysics models for nuclear reactors and analysis of uncertainties in those models. Reduced-order models (ROMs) provide a computationally cheaper alternative to compute uncertainties. However,
Elzohery Rabab, Roberts Jeremy
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Disease Models & Mechanisms, 2020 Duchenne muscular dystrophy (DMD) is a life-threatening neuromuscular disease caused by the lack of dystrophin, resulting in progressive muscle wasting and locomotor dysfunctions.
Tatianna Wai Ying Wong +13 more
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Xibei Gongye Daxue Xuebao, 2021 Low-frequency narrow-band noise is one of the important components in the slat noise. Based on the transient flow field analysis for multi-element airfoil 30P-30N, the main mode characteristics of the slat pressure fluctuation are analyzed by means of ...
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Journal of Comparative Effectiveness Research, 2020 Aim: Strategic Targeting of Registries and International Database of Excellence (STRIDE) is an ongoing, multicenter registry providing real-world evidence regarding ataluren use in patients with nonsense mutation Duchenne muscular dystrophy (nmDMD).
E. Mercuri +14 more
semanticscholar +1 more source
Biomarkers for Duchenne muscular dystrophy: myonecrosis, inflammation and oxidative stress
Disease Models & Mechanisms, 2020 Duchenne muscular dystrophy (DMD) is a lethal, X-linked disease that causes severe loss of muscle mass and function in young children. Promising therapies for DMD are being developed, but the long lead times required when using clinical outcome measures ...
Miranda D. Grounds +5 more
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Experimental Studies on Suppression of Combustion Instability with the Addition of Helium [PDF]
Journal of Applied Fluid Mechanics, 2022 When combustion instability occurs, fluctuation in the release of heat couples with oscillating pressure, while the sensitivity of flame to acoustic disturbance restricts the oscillation intensity.
Y. Liu, J. Li, Z. Tian, T. Zhang, Y. Yan
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