Results 121 to 130 of about 33,896 (240)

From emergence to replacement: The evolution of 3‐methylmethcathinone (3‐MMC) and its substitutes in the Dutch drug market (2012–2024)

open access: yesAddiction, EarlyView.
Abstract Background and aims The market for new psychoactive substances (NPS) is highly dynamic, with hundreds of substances emerging on the European drug market in the last decade. 3‐methylmethcathinone (3‐MMC), a synthetic cathinone and isomer of mephedrone (4‐MMC), gained popularity in the Netherlands due to its psychostimulant effects and initial ...
Nadia Robert Petronella Wilhelmina Hutten   +4 more
wiley   +1 more source

Optimization of Dimethyl Phthalate Degradation Parameters Using Zero-valent Iron Nanoparticles by Response Surface Methodology: Determination of Degradation Intermediate Products and Process Pathway

open access: yesJournal of Mazandaran University of Medical Sciences, 2018
Background and purpose: Phthalic acid esters (PAEs) are a group of organic compounds that are used as additives in plastic industry. Among PAEs, dimethyl phthalate (DMP), the simplest compound in phthalates, is an aromatic pollutant that disturbs ...
Samaneh Dehghan   +5 more
doaj  

Safety of Venom Immunotherapy in Pregnancy: A Multicentre Study

open access: yesAllergy, EarlyView.
Venom immunotherapy (VIT) during pregnancy, when maintenance dose is well tolerated, can be continued. No increased risk of adverse effects to VIT or safety concerns for the pregnancy or the newborns were observed. No decreased efficacy of VIT, in case of re‐stings, was reported.
Matteo Martini   +20 more
wiley   +1 more source

Data Management Plans (DMP)

open access: yes, 2016
Das Management von digitalen Daten und das Bereitstellen von Daten für Dritte ist eine zentrale Aufgabe der Wissenschaft und wird zunehmend von den Fördergebern verlangt.
Miksa, Tomasz   +2 more
core  

SERPINE1 Alternative Polyadenylation Influences Gastric Cancer Prognosis via N6‐Methyladenosine Modification

open access: yesCancer Science, EarlyView.
Multi‐omics integration of the transcriptomic APA landscape and m6A modifications identifies key prognostic genes. Their biological functions and molecular mechanisms in promoting tumor progression are comprehensively validated through in vitro assays. ABSTRACT Alternative polyadenylation (APA) and N6‐methyladenosine (m6A) methylation are critical post‐
Zhuoyi Wu   +6 more
wiley   +1 more source

Occupational Contact Allergy to Components of Epoxy Resin Systems: Descriptive and Comparative Epidemiological Analyses Based on IVDK Data 2008–2022

open access: yesContact Dermatitis, EarlyView.
This study analyzes patch test data from 23 969 patients with occupational dermatitis to characterise sensitization to bisphenol A diglycidyl ether (DGEBA), reactive diluents, and amine hardeners. The findings show an overall decline in DGEBA sensitization with fluctuations, substantial co‐sensitization, and markedly increased risks in construction ...
David Reissig   +9 more
wiley   +1 more source

The Role of Research Funders in Promoting Ethical International Health Research Collaborations

open access: yesDeveloping World Bioethics, EarlyView.
ABSTRACT Background International health research collaborations (IHRCs) between High Income countries (HICs) and Low‐and Middle‐Income Countries (LMICs) are essential in global health research, yet ethical challenges including the inequitable sharing of rewards and burdens among the research actors remain insufficiently addressed.
George Kwasi Barimah   +4 more
wiley   +1 more source

Cancer cell-selective ectopic expression of CD20 as an antigen enables rituximab repurposing for solid tumour immunotherapy. [PDF]

open access: yesClin Transl Med
A recombinant AAV delivered tumour gene therapy. NF‐κB drives tumour‐selective antigen (e.g., CD20) expression. Ectopic CD20 enables rituximab repurposing to solid tumours. ADCC, ADCP, and CDC contribute to the antitumour activity. Abstract Background Despite the clinical success of cancer immunotherapies, their efficacy is often compromised by antigen‐
Kong Z   +6 more
europepmc   +2 more sources

Data Management Plan (DMP) [PDF]

open access: yes
This data management plan (DMP) describes how the Safety through Disruption (Safe-D) National University Transportation Center (UTC) will comply with the U.S.
Virginia Polytechnic Institute and State University
core  

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