Results 151 to 160 of about 87,328 (317)

Covalent Attachment of a Platinum(II) Complex inside DNA Duplexes

ChemistryEurope, EarlyView.
Oxidative addition is used for the site‐specific incorporation of an organometallic PtII complex as an artificial nucleobase into a DNA duplex. The platination stabilizes the duplex and confers it with phosphorescence. An organometallic phosphorescent PtII complex is introduced into DNA duplexes via oxidative addition to a tailor‐made artificial ...
Tim Schäfer, Iván Maisuls, Felix Boisten, Marian Hebenbrock, Alexander Hepp, Cristian A. Strassert, Jens Müller   +6 more
wiley   +1 more source

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

Chemistry – A European Journal, EarlyView.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati, Claudio Trapella, Vinicio Zanirato, Virginia Cristofori, Anna Fantinati   +4 more
wiley   +1 more source

One‐Step and Universal Strategy for the Synthesis of Hypermodified Uracil Phosphoramidites acp3U and cmnm5U

Chemistry – A European Journal, EarlyView.
One‐step, highly efficient, and scalable synthesis of acp3U phosphoramidite is described, as well as a new alternative synthesis of cmnm5U phosphoramidite from a highly versatile intermediate. Latter could be scaled‐up, split, and aliquots turned simultaneously into cmnm5U, nm5U, and mnm5U.
Ewa Mejdr, Lena Heinickel, Thomas Carell, Ivana Mejdr   +3 more
wiley   +1 more source

Late‐Stage Phenylation From [13C6] and [2H5]Benzene: A Versatile Tool for Stable Isotope Labeled MS Standards

Chemistry – A European Journal, EarlyView.
ABSTRACT We explored aryl thianthrenation as a tool for directly incorporating multiple isotopes into molecular scaffolds starting from full isotopically labeled benzene. Stable isotope‐labeled (SIL) molecules are indispensable tools for investigating chemical and biological mechanisms and quantifying metabolites.
Alexandre Labiche, Bouchaib Mouhsine, Dorian Dupommier, Louise Fogel, Frédéric Robert, David‐Alexandre Buisson, Frédéric Taran, Davide Audisio   +7 more
wiley   +1 more source

Correlative Electron Paramagnetic Resonance Imaging and Atomic Force Microscopy of Lithium Deposited on Copper

ChemPhysChem, Volume 26, Issue 6, March 15, 2025.
The correlation of a spectroscopic (EPRI) and microscopic (AFM) technique is demonstrated for a sample of Li deposited on Cu. Areas of different morphology were analysed. The techniques complement each other's length scales as well as the information obtained from the sample.
Beatrice Wolff, Christian Hellenbrandt, Peter Jakes, Rüdiger‐A. Eichel, Josef Granwehr, Florian Hausen   +5 more
wiley   +1 more source

Structures of Native Doublet Microtubules from Trichomonas vaginalis Reveal Parasite-Specific Proteins

Nature Communications
Doublet microtubules (DMTs) are flagellar components required for the protist Trichomonas vaginalis (Tv) to swim through the human genitourinary tract to cause trichomoniasis, the most common non-viral sexually transmitted disease.
Alexander Stevens, Saarang Kashyap, Ethan H. Crofut, Shuqi E. Wang, Katherine A. Muratore, Patricia J. Johnson, Z. Hong Zhou   +6 more
doaj   +1 more source

Association of Neurodevelopmental Disorders and Congenital Anomalies With Prenatal Multiple Sclerosis Treatment—Real‐World Historical Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
There is a paucity of data regarding the effects of prenatal disease‐modifying therapies (DMTs) for multiple sclerosis (MS), on congenital anomalies in the offspring. Moreover, data on the association with neurodevelopmental disorders are lacking. This is an historical cohort study, within the Israeli Clalit Health Services database (2005–2024) that ...
Bar Rosh, Ofek Levi, Nili Stein, Amir Yahav, Naomi Gronich   +4 more
wiley   +1 more source

Comprehensive Analysis of the Degradation Phenomena of Proton Exchange Membrane Water Electrolyzers with Iridium on Antimony Tin Oxide Anodes

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study examines the structural and chemical evolution of low‐loaded Ir/ATO anodes during PEM water electrolysis under realistic conditions. Iridium dissolution is largely suppressed. In the early stages, both ionomer and support degradation are detected. Morphological reorganization occurs at the interface between the anode catalyst layer (ACL) and
Sambal Shashank Ambu, Nikolai Utsch, Tobias Morawietz, Maria Retuerto, Sergio Rojas, Oleg Usoltsev, Miriam Goll, Daniel García Sanchez, Andreas Glüsen, Aldo Saul Gago, Seyed Schwan Hosseiny, Kaspar Andreas Friedrich   +11 more
wiley   +1 more source

High‐Resolution Ion Mobility Approach for Rapid Determination of Multiple Human Milk Oligosaccharide Isomer Ratios

Helvetica Chimica Acta, EarlyView.
ABSTRACT This study presents a high‐throughput ion mobility approach that integrates flow injection analysis (FIA) with multiple stitched high‐resolution ion mobility ranges to enable comprehensive analysis of human milk oligosaccharide (HMO) isomer mixtures in a single acquisition.
Wenqing Xu, Estelle Rathahao‐Paris, Blanche Guillon, François Fenaille, Karine Adel‐Patient, Sandra Alves   +5 more
wiley   +1 more source

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima, Luiz Otávio Guimarães‐Ervilha, Isabela Pereira da Silva Bento, Renê Chagas da Silva, Mariana Machado‐Neves   +4 more
wiley   +1 more source