Results 251 to 260 of about 87,328 (317)

Long‐Term Clinical and Psychological Efficacy and Safety of Ocrelizumab in People With Multiple Sclerosis: A Real‐World Longitudinal Study

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Multiple sclerosis (MS) is the most prevalent immune‐mediated neurodegenerative disease affecting the central nervous system. Ocrelizumab, a humanized anti‐CD20 monoclonal antibody, has demonstrated significant efficacy in reducing disease activity and improving clinical outcomes of people with MS (PwMS) in clinical trials. However,
Majid Jafari, Mohammad Yazdan Panah, Saeed Vaheb, Iman Adibi, Fereshteh Ashtari, Vahid Shaygannejad, Aram Zabeti, Omid Mirmosayyeb   +7 more
wiley   +1 more source

The Putative RNA Methyltransferase Modulates T3SS Expression and Host NF-κB Activation via T6SS-Mediated Translocation in Pseudomonas aeruginosa. [PDF]

Int J Mol Sci
An Y, Lee Y, Jin Y, Wu W, Ha UH.
europepmc   +1 more source

Cluster of Severe Arginase 1 Deficiency in the Comoros: Clinical, Neuroimaging, and Molecular Features in 17 Patients From Mayotte Compared With 10 From Paris

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Arginase 1 deficiency (ARG1D) is the least common urea cycle disorder. Neonatal onset is rarely described, and hyperammonemic coma is less common in patients with ARG1D compared to other urea cycle disorders. In recent years, we diagnosed a high number of ARG1D patients in Mayotte, an insular (Comoro Islands) department of France.
Aurélie De Bruyne, Apolline Imbard, Charles‐Joris Roux, Abdourhahim Chamouine, Camille Schwab, Anaïs Brassier, Jean‐Baptiste Arnoux, Juliette Bouchereau, Cécile Laroche‐Raynaud, Tristan Mekdade, Margaux Gaschignard, Claire‐Marine Berat, Clément Pontoizeau, Stéphanie Gobin‐Limballe, Pascale de Lonlay, Jean‐François Benoist, Manuel Schiff   +16 more
wiley   +1 more source

Clinical Outcomes of Autologous Hematopoietic Stem Cell Transplantation in Filipino Patients With Multiple Sclerosis: A Single-Center Retrospective Case Series. [PDF]

Cureus
Dy JSH, Damian LF, Perez-Santiago C, Lopez F.   +3 more
europepmc   +1 more source

Genetic Diversity and Relationships Among Newly Developed Cowpea Mutant Lines Using SSR Markers and Agro‐Morphological Traits

Legume Science, Volume 8, Issue 1, March 2026.
ABSTRACT Cowpea (Vigna unguiculata [L.] Walp.) is a drought‐resilient and protein‐rich legume of major importance in arid and semiarid regions, including Eswatini, where it contributes to food, feed, and nutritional security. The objective of this study was to assess the genetic diversity and relationships among 30 cowpea genotypes, comprising 24 ...
Kwazi A. K. Mkhonta, Hussein Shimelis, Seltene Abady   +2 more
wiley   +1 more source

Determination and Confirmation of Psychedelic and Psychoactive Compounds in Botanical Materials by UPLC-ESI-MS/MS: Single-Laboratory Validation. [PDF]

J AOAC Int
French T, Fontana AJ, LaBudde R, Brunelle SL, Sudberg S.   +4 more
europepmc   +1 more source

Quantitative Systems Pharmacology Models of Anti‐Amyloid Treatments for Alzheimer's Disease: A Systematic Review

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.
ABSTRACT Quantitative systems pharmacology (QSP) models have emerged as useful tools for evaluating the efficacy of Alzheimer's disease (AD) therapies. Bringing together a clinical focus with the mechanistic detail of systems biology, QSP models are well suited to the complexity of AD and have been used to predict treatment outcomes and support ...
Lara Herriott, Mark Coles, Nicolas Fournier, Eamonn Gaffney, Jonathan Wagg   +4 more
wiley   +1 more source

Adult-onset and late-onset multiple sclerosis in older adults in a Finnish university hospital. [PDF]

Neurol Sci
Ahtinen K, Korhonen I, Kuusisto H, Rauma I.   +3 more
europepmc   +1 more source

The protection of mesenchymal stem cells in metabolic reprogramming and endothelial-mesenchymal transition in diabetic aortas. [PDF]

Stem Cells Transl Med
Ling M, He J, Jia X, Yu N, Song Y, Li X, Tang C, Yu W, Qiao H, Zhang C, Zhang Z, Ma T, Zhao C, Xing Y.   +13 more
europepmc   +1 more source

The predictive value of serum neurofilament light chain in achieving no evidence of disease activity-3 (NEDA-3) status in treatment-naïve patients with multiple sclerosis. [PDF]

J Neurol
Dimitriadou EM, Tzanetakos D, Theodorou A, Akrivaki A, Papadopoulos D, Mastorodemos V, Maleska A, Sotirli SA, Fakas N, Stergiou C, Kitsos D, Giannopapas V, Moschovos C, Giannopoulos S, Kuhle J, Tsivgoulis G, Tzartos JS.   +16 more
europepmc   +1 more source