Results 231 to 240 of about 28,987 (300)

Oligonucleotides Post‐Synthetic Modifications: An Overview of Clickable Nucleoside Phosphoramidites Suitable for Solid‐Phase Synthesis

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Clickable nucleoside phosphoramidites can be incorporated into oligonucleotides via solid‐phase synthesis (SPOS), enabling rapid and site‐specific post‐functionalization using bioorthogonal reactions. This review highlights their design, synthetic accessibility, and SPOS incorporation requirements, along with the kinetics and efficiency of post ...
Sébastien Depienne, Alexandra Bristiel, Dominique Urban, Dominique Guianvarc’h   +3 more
wiley   +1 more source

Pharmacokinetics and pharmacodynamics of intravenous and oral (S)‐ketamine: Investigating metabolite contribution to subjective effects

British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2260-2271, July 2026.
Aims Oral administration of (S)‐ketamine for treatment‐resistant depression (TRD), as alternative to the registered intranasal or off‐label intravenous administrations, has high potential. However, it is characterized by an extensive first‐pass metabolism, resulting in low (S)‐ketamine exposure and high levels of active metabolites, including (S ...
Marije E. Otto, Gabriël E. Jacobs, Joost C. van Mechelen, Laura G. J. M. Borghans, Johan G. C. van Hasselt, Linda B. S. Aulin   +5 more
wiley   +1 more source

Effect of Gold Nanoparticles as Co‐Catalyst on WO3/Cu2O Heterojunction Photoelectrodes to Enhance Light‐Driven CO2 Conversion Efficiency

ChemPhotoChem, Volume 10, Issue 7, July 2026.
The Ti/WO3/Cu2O/Au photoelectrode promotes efficient charge separation through a heterojunction structure, mainly when irradiated with a blue light LED, while Au acts as a cocatalyst and electron sink, enhancing interfacial charge transfer and improving the photoelectrocatalytic conversion of CO2 into methanol and methane.
João Angelo de Lima Perini, Lilian Danielle de Moura Torquato, João Pedro da Silva, Maria Valnice Boldrin Zanoni   +3 more
wiley   +1 more source

Evaluating use of disease-modifying therapies for multiple sclerosis using claims data. [PDF]

Front Health Serv
Wang X, Zhao FL, Newby D, Li S.
europepmc   +1 more source

Absence of significant hematologic abnormalities in breastfed infants of mothers with multiple sclerosis treated with anti-CD20 therapies. [PDF]

Mult Scler J Exp Transl Clin
Shah A, Alvarez E.
europepmc   +1 more source

Toxicometabolomics Characterization of Two N1-Sulfonated Dimethyltryptamine Derivatives in Zebrafish Larvae and Human Liver S9 Fractions Using Liquid Chromatography-High-Resolution Mass Spectrometry. [PDF]

Metabolites
Punnamraju P, Manier SK, Hemmer S, Grill M, Schippers P, Herrmann J, Meyer MR.   +6 more
europepmc   +1 more source

Combined Neuroprotective Effects of N,N-Dimethyltryptamine and Ventral Root Reimplantation Following Spinal Root Avulsion in Rats. [PDF]

J Neurochem
Aponte PAC, Montoya EH, Mazali IO, Sussulini A, Barraviera B, Ferreira RS, Cartarozzi LP, de Oliveira ALR.   +7 more
europepmc   +1 more source

Migration status, country of origin and long-term outcomes in multiple sclerosis: a Swedish nationwide study. [PDF]

J Neurol Neurosurg Psychiatry
Hedström AK, Olsson T, Alfredsson L.
europepmc   +1 more source

Treatment evolution in spinal muscular atrophy: insights from the SMArtCARE registry. [PDF]

Brain
Voigt-Müller C, Pfaffenlehner M, Bernert G, Cetin H, Hagenacker T, Kölbel H, Lochmüller H, Pfeuffer C, Vill K, Walter MC, Kirschner J, Pechmann A, SMArtCARE study group .   +12 more
europepmc   +1 more source