Results 221 to 230 of about 72,448 (283)

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, Volume 13, Issue 26, 8 May 2026.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Doped C₂₀ fullerenes as a new generation of efficient nanosorbents and nanosensors for rapid detection of dimethyltryptamine in drug detection. [PDF]

Sci Rep
Alharby TN, Alanazi M, Alanazi J.
europepmc   +1 more source

Cognitive function is associated with risk of conversion to secondary progressive multiple sclerosis: A cross-sectional study. [PDF]

PLoS One
Mirmosayyeb O, Mohammadi I, Rajai Firouzabadi S, Vaheb S, Yazdan Panah M, Fuchs TA, Weinstock-Guttman B, Shaygannejad V.   +7 more
europepmc   +1 more source

Comparative Effectiveness of Disease-Modifying Treatments in Double Seronegative Neuromyelitis Optica Spectrum Disorder. [PDF]

Neurol Neuroimmunol Neuroinflamm
Mahler JV, Vallejos GB, Mikami T, Bilodeau PA, Anderson M, Drosu N, Bobrowski-Khoury N, Silva GD, Solti M, Apóstolos-Pereira SL, Callegaro D, Leles Vieira de Souza B, Manzano GS, Vishnevetsky A, Gillani R, Pasquale O, Kim A, Vij R, Kister I, Gibbons EL, Jacob A, Huda S, Said Y, Krett JD, Sotirchos ES, Ramprasad M, Abboud H, Crelier VTC, Dos Santos G, Uawithya E, Siritho S, Sezen A, Altintas A, Gai F, Guo Y, Bhattacharyya S, Levy M, Matiello M.   +37 more
europepmc   +1 more source

Association of cytokine levels with treatment duration and patient family history in Egyptian multiple sclerosis patients. [PDF]

Sci Rep
Mohsen E, Haffez H, Ahmed S, El-Mahdy TS, Hamed S.   +4 more
europepmc   +1 more source

Psychedelic exposure in pregnancy: a scoping review to inform perinatal drug safety and clinical counseling. [PDF]

Ther Adv Drug Saf
Albert OM, Arthur A.
europepmc   +1 more source

Experiences of disease-modifying treatments in patients with multiple sclerosis - a qualitative study. [PDF]

BMC Neurol
Gottberg K, Kierkegaard M, Larsson BJ, Ytterberg C.   +3 more
europepmc   +1 more source

From Screening to Delivery of Disease‐Modifying Therapy: Real World Follow‐Up of Children With Early‐Stage Type 1 Diabetes

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 5379-5383, June 2026.
Theodora Papanikolaou, Josephine Elliott, Veer Sheth, Lauren M. Quinn, Parth Narendran, Renuka P. Dias   +5 more
wiley   +1 more source

Defining Acquired Hypothalamic Obesity: An Expert Call for Unified Diagnosis and Therapeutic Action

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4437-4441, June 2026.
Hanneke M. van Santen, Ashley H. Shoemaker, Mehul T. Dattani, Christian L. Roth, Mohamad Maghnie, Kevin C. J. Yuen, Christine Poitou, Hermann L. Müller   +7 more
wiley   +1 more source

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DMT+Harmine

2022
Basic research project with rodents. Rodents were administerred DMT and/or harmine and to investigate effects on 5HT2A receptor occupancy of DMT, changes in FDG uptake and brain concentrations of DMT, harmine and their metabolites. This work is published at Frontiers in Pharmacology (DOI: 10.3389/fphar.2023.1140656).
Scheidegger, Milan, Palner, Mikael, Egger, Klemens   +2 more
openaire   +1 more source