Results 21 to 30 of about 33,443 (169)

The Clustered Regularly Interspaced Short Palindromic Repeat System and Argonaute: An Emerging Bacterial Immunity System for Defense Against Natural Transformation?

Frontiers in Microbiology, 2020
Clustered regularly interspaced short palindromic repeat (CRISPR) systems and prokaryotic Argonaute proteins (Agos) have been shown to defend bacterial and archaeal cells against invading nucleic acids.
Mafeng Liu, Mafeng Liu, Mafeng Liu, Mi Huang, Mi Huang, Mi Huang, Mingshu Wang, Mingshu Wang, Mingshu Wang, Dekang Zhu, Dekang Zhu, Renyong Jia, Renyong Jia, Renyong Jia, Shun Chen, Shun Chen, Shun Chen, Ling Zhang, Ling Zhang, Leichang Pan, Leichang Pan, Anchun Cheng, Anchun Cheng, Anchun Cheng   +23 more
doaj   +1 more source

Specific DNA binding of archaeal histones HMfA and HMfB

Frontiers in Microbiology, 2023
In archaea, histones play a role in genome compaction and are involved in transcription regulation. Whereas archaeal histones bind DNA without sequence specificity, they bind preferentially to DNA containing repeats of alternating A/T and G/C motifs ...
Amanda M. Erkelens, Bram Henneman, Ramon A. van der Valk, Nancy C. S. Kirolos, Remus T. Dame, Remus T. Dame   +5 more
doaj   +1 more source

A highly conserved family of inactivated archaeal B family DNA polymerases

Biology Direct, 2008
A widespread and highly conserved family of apparently inactivated derivatives of archaeal B-family DNA polymerases is described. Phylogenetic analysis shows that the inactivated forms comprise a distinct clade among archaeal B-family polymerases and ...
Pavlov Youri I, Makarova Kira S, Rogozin Igor B, Koonin Eugene V   +3 more
doaj   +1 more source

Enzymatic Switching Between Archaeal DNA Polymerases Facilitates Abasic Site Bypass

Frontiers in Microbiology, 2021
Abasic sites are among the most abundant DNA lesions encountered by cells. Their replication requires actions of specialized DNA polymerases. Herein, two archaeal specialized DNA polymerases were examined for their capability to perform translesion DNA ...
Xu Feng, Baochang Zhang, Ruyi Xu, Zhe Gao, Xiaotong Liu, Guanhua Yuan, Sonoko Ishino, Mingxia Feng, Yulong Shen, Yoshizumi Ishino, Qunxin She   +10 more
doaj   +1 more source

Solution structure of an archaeal DNA binding protein with an eukaryotic zinc finger fold. [PDF]

PLoS ONE, 2013
While the basal transcription machinery in archaea is eukaryal-like, transcription factors in archaea and their viruses are usually related to bacterial transcription factors.
Florence Guillière, Chloé Danioux, Carole Jaubert, Nicole Desnoues, Muriel Delepierre, David Prangishvili, Guennadi Sezonov, J Iñaki Guijarro   +7 more
doaj   +1 more source

Site‐Specific Protein Bioconjugation Through Cellular Incorporation of Noncanonical Amino Acids

Angewandte Chemie, EarlyView.
Genetic code expansion (GCE) enables site‐specific installation of noncanonical amino acids containing bioorthogonal conjugation handles, allowing precise, homogeneous protein modification. This review examines the principles of orthogonal translation, surveys the chemistries available for chemoselective labeling, and highlights emerging multi‐site ...
Rahul Sarkar, Manas Joshi, Abhishek Chatterjee   +2 more
wiley   +2 more sources

Genotyping

Egyptian Journal of Aquatic Research, 2014
Culture-independent 16S rRNA gene analysis approach was used to explore and evaluate archaea in a polluted site, El-Zeitia, Suez Gulf, Egypt. Metagenomic DNA was extracted from a sediment sample.
Hosam Easa Elsaied
doaj   +1 more source

The Epigenomic Landscape of Prokaryotes. [PDF]

PLoS Genetics, 2016
DNA methylation acts in concert with restriction enzymes to protect the integrity of prokaryotic genomes. Studies in a limited number of organisms suggest that methylation also contributes to prokaryotic genome regulation, but the prevalence and ...
Matthew J Blow, Tyson A Clark, Chris G Daum, Adam M Deutschbauer, Alexey Fomenkov, Roxanne Fries, Jeff Froula, Dongwan D Kang, Rex R Malmstrom, Richard D Morgan, Janos Posfai, Kanwar Singh, Axel Visel, Kelly Wetmore, Zhiying Zhao, Edward M Rubin, Jonas Korlach, Len A Pennacchio, Richard J Roberts   +18 more
doaj   +1 more source

Architectures of archaeal GINS complexes, essential DNA replication initiation factors

BMC Biology, 2011
Background In the early stage of eukaryotic DNA replication, the template DNA is unwound by the MCM helicase, which is activated by forming a complex with the Cdc45 and GINS proteins.
Saito Mihoko, Nagasawa Naoko, Mayanagi Kouta, Shirai Tsuyoshi, Ogino Hiromi, Fujino Seiji, Ishino Sonoko, Oyama Takuji, Ishino Yoshizumi, Morikawa Kosuke   +9 more
doaj   +1 more source

Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol ε and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors

Biology Direct, 2009
Background Evolution of DNA polymerases, the key enzymes of DNA replication and repair, is central to any reconstruction of the history of cellular life.
Pavlov Youri I, Rogozin Igor B, Makarova Kira S, Tahirov Tahir H, Koonin Eugene V   +4 more
doaj   +1 more source