Results 191 to 200 of about 1,269,047 (286)

Shedding Light on the Cellular Uptake Mechanisms of Bioactive Glass Nanoparticles as Controlled Intracellular Delivery Platforms: A Review of the Recent Literature

open access: yesAdvanced Healthcare Materials, EarlyView.
This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda   +1 more
wiley   +1 more source

Clinical isolates of <i>Providencia rettgeri</i> and <i>Providencia Stuartii</i> evades neutrophil-mediated killing by subverting neutrophil-extracellular traps. [PDF]

open access: yesFront Immunol
Castro JE   +9 more
europepmc   +1 more source

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

open access: yesAdvanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji   +8 more
wiley   +1 more source

In silico-derived <i>Actinobacillus equuli</i>-specific DNA markers and development of associated PCR assays. [PDF]

open access: yesJ Vet Diagn Invest
Songsungthong W   +3 more
europepmc   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao   +2 more
wiley   +1 more source

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

open access: yesAdvanced Healthcare Materials, EarlyView.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor   +12 more
wiley   +1 more source

Transformative Bioactive Wear Resistant Ti3Au:N and Ti3Au:O Coatings for Medical Implants and Devices

open access: yesAdvanced Healthcare Materials, EarlyView.
Coatings of titanium‐gold are grown in nitrogen and oxygen environments via magnetron sputtering to simultaneously enhance their biotribological and antibacterial properties. The coatings are highly crystalline with superhard scratch‐resistant surfaces and wear rates 20 times lower than the bare Ti‐6Al‐4V substrate.
Cecil Cherian Lukose   +11 more
wiley   +1 more source

Temporal succession of bacterial and archaeal communities in a Mediterranean high-mountain lake over the last 430 years using sedimentary DNA. [PDF]

open access: yesMicrob Ecol
Castellano-Hinojosa A   +6 more
europepmc   +1 more source

Living Materials Approach for In Situ Bio‐Polymers Production Using Bacillus Paralicheniformis in Microneedles

open access: yesAdvanced Healthcare Materials, EarlyView.
Dissolvable microneedle (MN) device containing Bacillus paralicheniformis. The polymeric matrix encapsulates and protects the bacteria, preserving their viability while enabling in situ production and release of γ‐polyglutamic acid. The bacteria are delivered into the skin via 500 µm‐long microneedles, and remain detectable on the skin 24 h post ...
Caroline Hali Alperovitz   +3 more
wiley   +1 more source

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