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DNA vaccines for bacterial infections
Immunology & Cell Biology, 1997 DNA vaccines are an exciting development in vaccine technology which may have a special role in preventing viral infections and as ‘theracines’ for cancer. Their use in preventing bacterial infections has, by comparison, been less well documented.
Strugnell, RA +7 more
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An efficient strategy for broad-range detection of low abundance bacteria without DNA decontamination of PCR reagents. [PDF]
PLoS ONE, 2011 BACKGROUND: Bacterial DNA contamination in PCR reagents has been a long standing problem that hampers the adoption of broad-range PCR in clinical and applied microbiology, particularly in detection of low abundance bacteria.
Shy-Shin Chang +3 more
doaj +1 more source
Bacterial Extracellular DNA Promotes β-Amyloid Aggregation
Microorganisms, 2021 Alzheimer’s disease is associated with prion-like aggregation of the amyloid β (Aβ) peptide and the subsequent accumulation of misfolded neurotoxic aggregates in the brain.
George Tetz, Victor Tetz
doaj +1 more source
, 2010 Some bacterial and viral DNA sequences have been found to induce low frequency electromagnetic waves in high aqueous dilutions. This phenomenon appears to be triggered by the ambient electromagnetic background of very low frequency.
A Tedeschi +12 more
core +1 more source
Frontiers in Microbiology, 2020 Infection and inflammation are well recognized causes of spontaneous preterm delivery (PTD) (<37 gestational weeks) and adverse infant outcomes. To date, there has been very little investigation into bacterial communities in amniotic fluid using next ...
Lisa Stinson +14 more
doaj +1 more source
Antimicrobial activity of an iron triple helicate [PDF]
, 2009 The prevalence of antibiotic resistance has resulted in the need for new approaches to be developed to combat previously easily treatable infections.
Adair D. Richards +15 more
core +1 more source
The human gut bacterial genotoxin colibactin alkylates DNA
Science, 2019 Bacterial warhead targets DNA The bacterial toxin colibactin causes double-stranded DNA breaks and is associated with the occurrence of bacterially induced colorectal cancer in humans. However, isolation of colibactin is difficult, and its mode of action
Matthew R. Wilson +13 more
semanticscholar +1 more source
CpG DNA analysis of bacterial STDs [PDF]
BMC Infectious Diseases, 2015 Bacterial infections in the genital tract frequently result in morbidity through a variety of inflammation based symptoms. One component of the bacteria that may trigger host inflammatory response is their DNA. CpG motifs in this DNA are known targets for Toll-like receptor 9 (TLR9), which is a pathogen-recognition receptors focusing on CpG DNA.
M. Singer +4 more
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Superstatistical model of bacterial DNA architecture [PDF]
Scientific Reports, 2017 AbstractUnderstanding the physical principles that govern the complex DNA structural organization as well as its mechanical and thermodynamical properties is essential for the advancement in both life sciences and genetic engineering. Recently we have discovered that the complex DNA organization is explicitly reflected in the arrangement of nucleotides
Bogachev M. +3 more
openaire +4 more sources
Transferrin-polycation conjugates as carriers for DNA uptake into cells. [PDF]
, 1990 We have developed a high-efficiency nucleic acid delivery system that uses receptor-mediated endocytosis to carry DNA macromolecules into cells. We accomplished this by conjugating the iron-transport protein transferrin to polycations that bind nucleic ...
Beug, Hartmut +4 more
core +1 more source