Results 41 to 50 of about 1,303,684 (303)

DNA vaccines for bacterial infections

open access: yesImmunology & Cell Biology, 1997
DNA vaccines are an exciting development in vaccine technology which may have a special role in preventing viral infections and as ‘theracines’ for cancer. Their use in preventing bacterial infections has, by comparison, been less well documented.
Strugnell, RA   +7 more
openaire   +4 more sources

Bacterial Extracellular DNA Promotes β-Amyloid Aggregation

open access: yesMicroorganisms, 2021
Alzheimer’s disease is associated with prion-like aggregation of the amyloid β (Aβ) peptide and the subsequent accumulation of misfolded neurotoxic aggregates in the brain.
George Tetz, Victor Tetz
doaj   +1 more source

Indirect DNA extraction method suitable for acidic soil with high clay content

open access: yesMethodsX, 2018
DNA extraction is an essential procedure when investigating microbial communities in environmental samples by sequencing technologies. High clay soils can be problematic as DNA adsorbs to the clay particles and can thereby be preserved from lysed, non ...
Eva Högfors-Rönnholm   +3 more
doaj   +1 more source

Is there a placental microbiota? A critical review and re-analysis of published placental microbiota datasets

open access: yesBMC Microbiology, 2023
The existence of a placental microbiota is debated. The human placenta has historically been considered sterile and microbial colonization was associated with adverse pregnancy outcomes.
Jonathan J. Panzer   +6 more
doaj   +1 more source

TLR9 mediates S. aureus killing inside osteoblasts via induction of oxidative stress [PDF]

open access: yes, 2016
Background: Staphylococcus aureus is the principle causative pathogen of osteomyelitis and implant-associated bone infections. It is able to invade and to proliferate inside osteoblasts thus avoiding antibiotic therapy and the host immune system ...
Alt, Volker   +7 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Genome-wide identification of essential genes in the invasive Streptococcus anginosus strain

open access: yesScientific Reports
Streptococcus anginosus, part of the Streptococcus anginosus group (SAG), is a human commensal increasingly recognized as an opportunistic pathogen responsible for abscesses formation and infections, also invasive ones.
Aleksandra Kuryłek   +4 more
doaj   +1 more source

A newly identified IncY plasmid from multi-drug-resistant Escherichia coli isolated from dairy cattle feces in Poland

open access: yesMicrobiology Spectrum
Comprehensive whole-genome sequencing was performed on two multi-drug-resistant Escherichia coli strains isolated from cattle manure from a typical dairy farm in Poland in 2020.
Magdalena Zalewska   +7 more
doaj   +1 more source

Optimizing bacterial DNA extraction in urine.

open access: yesPLoS ONE, 2019
Urine is an acceptable, non-invasive sample for investigating the human urogenital microbiota and for the diagnosis of sexually transmitted infections.
Matthew M Munch   +6 more
doaj   +1 more source

Inflating bacterial cells by increased protein synthesis. [PDF]

open access: yes, 2015
Understanding how the homeostasis of cellular size and composition is accomplished by different organisms is an outstanding challenge in biology. For exponentially growing Escherichia coli cells, it is long known that the size of cells exhibits a strong ...
Basan, Markus   +6 more
core   +2 more sources

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