Results 31 to 40 of about 3,376,191 (316)

Lipid bilayer-assisted dynamic self-assembly of hexagonal DNA origami blocks into monolayer crystalline structures with designed geometries

open access: yesiScience, 2022
Summary: The DNA origami technique is used to construct custom-shaped nanostructures that can be used as components of two-dimensional crystalline structures with user-defined structural patterns.
Yuki Suzuki   +3 more
doaj   +1 more source

High Sensitivity DNA Detection Using Gold Nanoparticle Functionalised Polyaniline Nanofibres [PDF]

open access: yes, 2010
Polyaniline (PANI) nanofibres (PANI-NF) have been modified with chemically grown gold nanoparticles to give a nanocomposite material (PANI-NF–AuNP) and deposited on gold electrodes. Single stranded capture DNA was then bound to the gold nanoparticles and
Barry, Thomas   +8 more
core   +1 more source

Fabrication of porcine DNA biosensor based on ruthenium bipyridine complex [PDF]

open access: yes, 2016
Electrochemical DNA biosensor for detection of porcine oligonucleotides based on ruthenium (II) as label redox complex has been developed. The system of biosensor is based on the modified screen printed carbon electrode (SPE) with goldnanoparticles ...
Abd Karim, Nurul Huda   +5 more
core   +1 more source

RNA-programmed genome editing in human cells

open access: yeseLife, 2013
Type II CRISPR immune systems in bacteria use a dual RNA-guided DNA endonuclease, Cas9, to cleave foreign DNA at specific sites. We show here that Cas9 assembles with hybrid guide RNAs in human cells and can induce the formation of double-strand DNA ...
Martin Jinek   +5 more
doaj   +1 more source

Phase Transition of DNA-Linked Gold Nanoparticle

open access: yes, 2002
Melting and hybridization of DNA-capped gold nanoparticle networks are investigated with optical absorption spectroscopy. Single-stranded, 12-base DNA-capped gold nanoparticles are linked with complementary, single-stranded, 24-base linker DNA to form ...
Ching-Hwa Kiang   +14 more
core   +1 more source

Simplified detection of the hybridized DNA using a graphene field effect transistor

open access: yesScience and Technology of Advanced Materials, 2017
Detection of disease-related gene expression by DNA hybridization is a useful diagnostic method. In this study a monolayer graphene field effect transistor (GFET) was fabricated for the detection of a particular single-stranded DNA (target DNA).
Arun Kumar Manoharan   +3 more
doaj   +1 more source

Ion-Channel Genosensor for the Detection of Specific DNA Sequences Derived from Plum Pox Virus in Plant Extracts

open access: yesSensors, 2014
A DNA biosensor for detection of specific oligonucleotides sequences of Plum Pox Virus (PPV) in plant extracts and buffer is proposed. The working principles of a genosensor are based on the ion-channel mechanism. The NH2-ssDNA probe was deposited onto a
Kamila Malecka   +3 more
doaj   +1 more source

Factors Impacting Invader-Mediated Recognition of Double-Stranded DNA

open access: yesMolecules, 2022
The development of chemically modified oligonucleotides enabling robust, sequence-unrestricted recognition of complementary chromosomal DNA regions has been an aspirational goal for scientists for many decades.
Caroline P. Shepard   +3 more
doaj   +1 more source

Impedimetric DNA Biosensor Based on a Nanoporous Alumina Membrane for the Detection of the Specific Oligonucleotide Sequence of Dengue Virus

open access: yesSensors, 2013
A novel and integrated membrane sensing platform for DNA detection is developed based on an anodic aluminum oxide (AAO) membrane. Platinum electrodes (~50–100 nm thick) are coated directly on both sides of the alumina membrane to eliminate the solution ...
Chee-Seng Toh, Jiajia Deng
doaj   +1 more source

Bubble propagation in a helicoidal molecular chain

open access: yes, 2000
We study the propagation of very large amplitude localized excitations in a model of DNA that takes explicitly into account the helicoidal structure. These excitations represent the ``transcription bubble'', where the hydrogen bonds between complementary
A. Campa   +30 more
core   +1 more source

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