Results 21 to 30 of about 491,145 (311)

Complementary DNA Libraries and Neurological Disease [PDF]

Archives of Neurology, 1998
The DNA in our cell nuclei contains all the information necessary to direct our biological functions. The gene is 1 unit of such information that usually specifies the expression of 1 protein product. A detailed knowledge of each gene will enable us to understand disease at the molecular level.
B, Joseph, H, Furneaux
openaire   +2 more sources

Electrochemical Detection of Single Nucleotide Polymorphism in Short DNA Sequences Related To Cattle Fatty Acid Binding Protein 4 Gene

International Journal of Electrochemical Science, 2012
Electrochemical nucleic acid biosensor for detection of single nucleotide polymorphism (SNP) in Fatty acid binding protein 4 (FABP4) has been developed by immobilization of single stranded thiolated probe DNA (ss-DNA-SH) onto gold surfaces (ss-DNA-SH/Au)
Venu Reddy, Torati Sri Ramulu, Brajalal Sinha, Jaein Lim, Md. Rashedul Hoque, Jun-Heon Lee, ChoelGi Kim   +6 more
doaj   +1 more source

Experimental validation of determinants of UV sensitivity using synthetic DNA

Journal of Photochemistry and Photobiology, 2022
Treatment with ultraviolet (UV) light has been shown to be effective for disinfection of pathogens. For pathogenic risk management, it would be effective to estimate the UV sensitivity of unknown pathogenic microorganisms from their nucleotide sequences.
M. Otaki, Y. Higashino, Y. Yamada
doaj   +1 more source

Cloning of human thyroglobulin complementary DNA [PDF]

FEBS Letters, 1982
info:eu-repo/semantics ...
Brocas, Huguette, Christophe, Daniel, Pohl, Viviane, Vassart, Gilbert   +3 more
openaire   +3 more sources

In Vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases [PDF]

, 2012
The enzymatic control of the setting and maintenance of symmetric and non-symmetric DNA methylation patterns in a particular genome context is not well understood.
Julia Arand (155279), Meissner, A, Meilinger, D., Arand, Julia, Leonhardt, Heinrich, Jenuwein, Thomas, Wolf, Verena, Thomas Jenuwein (70681), Tommy Karius, David Spieler, Jenuwein, T., Xu, G, Tommy Karius (155285), Walter, Jörn, Wolf, V., Branco, MR, Leonhardt, H, Spieler, D, Branco, Miguel R., Meilinger, Daniela, Julia Arand, Jörn Walter, Walter, Joern, Jörn Walter (37094), Walter, J, Miguel R. Branco (42502), Verena Wolf, Karius, T, Meissner, Alexander, Arand, J, Alexander Meissner (11643), Meilinger, D, Daniela Meilinger, Heinrich Leonhardt (18589), Verena Wolf (155286), Daniela Meilinger (107843), Arand, J., Jenuwein, T, Miguel R Branco, Thomas Jenuwein, Guoliang Xu, Alexander Meissner, Walter, J., Meissner, A., Heinrich Leonhardt, Karius, Tommy, Guoliang Xu (67200), Spieler, David, Karius, T., Xu, Guoliang, David Spieler (155282), Branco, M., Xu, G., Wolf, V, Spieler, D., Leonhardt, H.   +55 more
core   +1 more source

HLA genotyping by next-generation sequencing of complementary DNA

BMC Genomics, 2017
Background Genotyping of the human leucocyte antigen (HLA) is indispensable for various medical treatments. However, unambiguous genotyping is technically challenging due to high polymorphism of the corresponding genomic region.
Hidenobu Segawa, Yoji Kukita, Kikuya Kato   +2 more
doaj   +1 more source

Titanium Dioxide Nanoparticle-Based Interdigitated Electrodes: A Novel Current to Voltage DNA Biosensor Recognizes E. coli O157:H7. [PDF]

PLoS ONE, 2015
Nanoparticle-mediated bio-sensing promoted the development of novel sensors in the front of medical diagnosis. In the present study, we have generated and examined the potential of titanium dioxide (TiO2) crystalline nanoparticles with aluminium ...
Sh Nadzirah, N Azizah, Uda Hashim, Subash C B Gopinath, Mohd Kashif   +4 more
doaj   +1 more source

The Enhanced Sensitivity of a Porous Silicon Microcavity Biosensor Based on an Angular Spectrum Using CdSe/ZnS Quantum Dots

Sensors, 2019
To improve the detection sensitivity of porous silicon microcavity biosensors, CdSe/ZnS quantum dots are used to label complementary DNA molecules for the refractive index amplification and angular spectrum method for detection.
Rui Zhou, Zhenhong Jia, Xiaoyi Lv, Xiaohui Huang   +3 more
doaj   +1 more source

Mechanical separation of the complementary strands of DNA [PDF]

Proceedings of the National Academy of Sciences, 1997
We describe the mechanical separation of the two complementary strands of a single molecule of bacteriophage λ DNA. The 3′ and 5′ extremities on one end of the molecule are pulled progressively apart, and this leads to the opening of the double helix. The typical forces along the opening are in the range of 10–15 pN. The separation force signal is
B, Essevaz-Roulet, U, Bockelmann, F, Heslot   +2 more
openaire   +2 more sources

Inhibition of BRCA2 and Thymidylate Synthase Creates Multidrug Sensitive Tumor Cells via the Induction of Combined “Complementary Lethality”

Molecular Therapy: Nucleic Acids, 2013
A high mutation rate leading to tumor cell heterogeneity is a driver of malignancy in human cancers. Paradoxically, however, genomic instability can also render tumors vulnerable to therapeutic attack. Thus, targeting DNA repair may induce an intolerable
Mateusz Rytelewski, Peter J Ferguson, Saman Maleki Vareki, Rene Figueredo, Mark Vincent, James Koropatnick   +5 more
doaj   +1 more source