Results 21 to 30 of about 474,811 (267)
Complementary DNA Libraries and Neurological Disease [PDF]
Archives of Neurology, 1998 The DNA in our cell nuclei contains all the information necessary to direct our biological functions. The gene is 1 unit of such information that usually specifies the expression of 1 protein product. A detailed knowledge of each gene will enable us to understand disease at the molecular level.
B, Joseph, H, Furneaux
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Cloning of human thyroglobulin complementary DNA [PDF]
FEBS Letters, 1982 info:eu-repo/semantics ...
Brocas, Huguette +3 more
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Coding capacity of complementary DNA strands [PDF]
Nucleic Acids Research, 1981 A Fortran computer algorithm has been used to analyze the nucleotide sequence of several structural genes. The analysis performed on both coding and complementary DNA strands shows that whereas open reading frames shorter than 100 codons are randomly distributed on both DNA strands, open reading frames longer than 100 codons ("virtual genes") are ...
Casino A. +5 more
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HLA genotyping by next-generation sequencing of complementary DNA
BMC Genomics, 2017 Background Genotyping of the human leucocyte antigen (HLA) is indispensable for various medical treatments. However, unambiguous genotyping is technically challenging due to high polymorphism of the corresponding genomic region.
Hidenobu Segawa +2 more
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Titanium Dioxide Nanoparticle-Based Interdigitated Electrodes: A Novel Current to Voltage DNA Biosensor Recognizes E. coli O157:H7. [PDF]
PLoS ONE, 2015 Nanoparticle-mediated bio-sensing promoted the development of novel sensors in the front of medical diagnosis. In the present study, we have generated and examined the potential of titanium dioxide (TiO2) crystalline nanoparticles with aluminium ...
Sh Nadzirah +4 more
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Sensors, 2019 To improve the detection sensitivity of porous silicon microcavity biosensors, CdSe/ZnS quantum dots are used to label complementary DNA molecules for the refractive index amplification and angular spectrum method for detection.
Rui Zhou +3 more
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Molecular Therapy: Nucleic Acids, 2013 A high mutation rate leading to tumor cell heterogeneity is a driver of malignancy in human cancers. Paradoxically, however, genomic instability can also render tumors vulnerable to therapeutic attack. Thus, targeting DNA repair may induce an intolerable
Mateusz Rytelewski +5 more
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Mechanical separation of the complementary strands of DNA [PDF]
Proceedings of the National Academy of Sciences, 1997 We describe the mechanical separation of the two complementary strands of a single molecule of bacteriophage λ DNA. The 3′ and 5′ extremities on one end of the molecule are pulled progressively apart, and this leads to the opening of the double helix. The typical forces along the opening are in the range of 10–15 pN. The separation force signal is
B, Essevaz-Roulet +2 more
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F1000Research, 2014 Conventionally, in a polymerase chain reaction (PCR), oligonucleotide primers bind to the template DNA in an antiparallel complementary way and the template DNA is amplified as it is.
Vikash Bhardwaj, Kulbhushan Sharma
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Scientific Reports, 2023 The tetrameric tumor suppressor p53 represents a great challenge for 3D-structural analysis due to its high degree of intrinsic disorder (ca. 40%). We aim to shed light on the structural and functional roles of p53’s C-terminal region in full-length ...
Alessio Di Ianni +8 more
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