Results 21 to 30 of about 804,751 (297)

Cloning of human thyroglobulin complementary DNA [PDF]

FEBS Letters, 1982
Journal Article ; Research Support, Non-U.S.
Brocas, Huguette, Christophe, Daniel, Pohl, Viviane, Vassart, Gilbert   +3 more
openaire   +2 more sources

The Enhanced Sensitivity of a Porous Silicon Microcavity Biosensor Based on an Angular Spectrum Using CdSe/ZnS Quantum Dots

Sensors, 2019
To improve the detection sensitivity of porous silicon microcavity biosensors, CdSe/ZnS quantum dots are used to label complementary DNA molecules for the refractive index amplification and angular spectrum method for detection.
Rui Zhou, Zhenhong Jia, Xiaoyi Lv, Xiaohui Huang   +3 more
doaj   +1 more source

Linker-mediated self-assembly of mobile DNA-coated colloids

, 2020
Developing construction methods of materials tailored for given applications with absolute control over building block placement poses an immense challenge.
Ciamarra, Massimo Pica, Hu, Hao, Ni, Ran, Xia, Xiuyang   +3 more
core   +1 more source

Structural basis for CRISPR RNA-guided DNA recognition by Cascade [PDF]

, 2011
The CRISPR (clustered regularly interspaced short palindromic repeats) immune system in prokaryotes uses small guide RNAs to neutralize invading viruses and plasmids.
A Bolotin, A Noy, AJR Heck, AL Gnatt, Albert J R Heck, AM Maxam, Ambrosius P L Snijders, Arjan Barendregt, B Wiedenheft, Blake Wiedenheft, C Hale, C Pourcel, CR Hale, D Han, DH Haft, DY Lee, Edze R Westra, Egbert J Boekema, Esther van Duijn, FJ Mojica, FJ Mojica, FV Karginov, GT Oostergetel, H Deveau, H Deveau, J Carte, J Li, J van der Oost, JB Ma, JE Garneau, Jelle B Bultema, Jennifer A Doudna, John van der Oost, K Lorenzen, K Yu, Kaihong Zhou, KS Makarova, LA Marraffini, LA Marraffini, LA Marraffini, M Thomas, M van Heel, M Zhou, Magnus Lundgren, Marieke R Beijer, Mark J Dickman, Matthijs M Jore, MJ Dickman, MR Singleton, N Tahallah, P Horvath, P Horvath, R Barrangou, R Jansen, RE Haurwitz, Reinhild Wurm, RH van den Heuvel, RK Lillestøl, Rolf Wagner, S Houwing, Sakharam P Waghmare, SC Raghavan, SJ Brouns, SP Waghmare, Stan J J Brouns, T Itoh, T Wilson-Sali, TA Baker, TH Tang, V Kunin, Y Agari, Ümit Pul   +71 more
core   +5 more sources

Fabrication and functionalization of PCB gold electrodes suitable for DNA-based electrochemical sensing [PDF]

, 2014
The request of high specificity and selectivity sensors suitable for mass production is a constant demand in medical research. For applications in point-of-care diagnostics and therapy, there is a high demand for low cost and rapid sensing platforms ...
Dhaenens, Kristof, Gielen, An, Henry, OYF, Lundeberg, J, O'Sullivan, CK, Salvo, Pietro, Sanchez, JLA, Solnestam, BW, Vanfleteren, Jan   +8 more
core   +1 more source

Inhibition of BRCA2 and Thymidylate Synthase Creates Multidrug Sensitive Tumor Cells via the Induction of Combined “Complementary Lethality”

Molecular Therapy: Nucleic Acids, 2013
A high mutation rate leading to tumor cell heterogeneity is a driver of malignancy in human cancers. Paradoxically, however, genomic instability can also render tumors vulnerable to therapeutic attack. Thus, targeting DNA repair may induce an intolerable
Mateusz Rytelewski, Peter J Ferguson, Saman Maleki Vareki, Rene Figueredo, Mark Vincent, James Koropatnick   +5 more
doaj   +1 more source

High Sensitivity DNA Detection Using Gold Nanoparticle Functionalised Polyaniline Nanofibres [PDF]

, 2010
Polyaniline (PANI) nanofibres (PANI-NF) have been modified with chemically grown gold nanoparticles to give a nanocomposite material (PANI-NF–AuNP) and deposited on gold electrodes. Single stranded capture DNA was then bound to the gold nanoparticles and
Barry, Thomas, Forster, Robert J., Kaner, Richard B., Keyes, Tia E., Kojima, Robert, Lacey, Katrina, O'Grady, Justin, Spain, Elaine, Wallace, Gordon G.   +8 more
core   +1 more source

Parallel DNA polymerase chain reaction: Synthesis of two different PCR products from a DNA template [v1; ref status: indexed, http://f1000r.es/4sm]

F1000Research, 2014
Conventionally, in a polymerase chain reaction (PCR), oligonucleotide primers bind to the template DNA in an antiparallel complementary way and the template DNA is amplified as it is.
Vikash Bhardwaj, Kulbhushan Sharma
doaj   +1 more source

Structural assessment of the full-length wild-type tumor suppressor protein p53 by mass spectrometry-guided computational modeling

Scientific Reports, 2023
The tetrameric tumor suppressor p53 represents a great challenge for 3D-structural analysis due to its high degree of intrinsic disorder (ca. 40%). We aim to shed light on the structural and functional roles of p53’s C-terminal region in full-length ...
Alessio Di Ianni, Christian Tüting, Marc Kipping, Christian H. Ihling, Janett Köppen, Claudio Iacobucci, Christian Arlt, Panagiotis L. Kastritis, Andrea Sinz   +8 more
doaj   +1 more source

Crowding-induced hybridization of single DNA hairpins [PDF]

, 2015
It is clear that a crowded environment influences the structure, dynamics, and interactions of biological molecules, but the complexity of this phenomenon demands the development of new experimental and theoretical approaches.
Baltierra-Jasso, Laura E., Laflor, Linda, Magennis, Steven W., Morten, Michael J., Quinn, Steven D.   +4 more
core   +2 more sources