Results 31 to 40 of about 491,145 (311)
Complementary recognition in condensed DNA: Accelerated DNA renaturation [PDF]
Journal of Molecular Biology, 1991 The functional consequences of DNA condensation are investigated. The recognition of complementary strands is profoundly modified by this critical phenomenon. (1) Condensation of denatured DNA greatly accelerates the kinetics of DNA renaturation. We propose a unifying explanation for the effects of several accelerating solvents studied here including ...
J L, Sikorav, G M, Church
openaire +2 more sources
F1000Research, 2014 Conventionally, in a polymerase chain reaction (PCR), oligonucleotide primers bind to the template DNA in an antiparallel complementary way and the template DNA is amplified as it is.
Vikash Bhardwaj, Kulbhushan Sharma
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Scientific Reports, 2023 The tetrameric tumor suppressor p53 represents a great challenge for 3D-structural analysis due to its high degree of intrinsic disorder (ca. 40%). We aim to shed light on the structural and functional roles of p53’s C-terminal region in full-length ...
Alessio Di Ianni +8 more
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Efficiency of peptide nucleic acid-directed PCR clamping and its application in the investigation of natural diets of the Japanese eel leptocephali. [PDF]
PLoS ONE, 2011 Polymerase chain reaction (PCR)-clamping using blocking primer and DNA-analogs, such as peptide nucleotide acid (PNA), may be used to selectively amplify target DNA for molecular diet analysis.
Takeshi Terahara +7 more
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Complementary-DNA-Strand Cross-Linked Polyacrylamide Hydrogels
, 2019 We examine networks of complementary-DNA-strand cross-linked polyacrylamide, with and without covalent N,N′-methylene(bis)acrylamide cross-linking, using rheological time–temperature superposition (TTS) to ascertain how temperature and composition ...
Reghan J. Hill (1526266) +3 more
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, 1998 Background: The structural and conformational variety in nucleic acid complexes is largely controlled by the sugar-phosphate backbone. In order to modulate specific features such as strength or selectivity of complex formation by designing nucleotide ...
Epple, C. +2 more
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RNA-programmed genome editing in human cells
eLife, 2013 Type II CRISPR immune systems in bacteria use a dual RNA-guided DNA endonuclease, Cas9, to cleave foreign DNA at specific sites. We show here that Cas9 assembles with hybrid guide RNAs in human cells and can induce the formation of double-strand DNA ...
Martin Jinek +5 more
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iScience, 2022 Summary: The DNA origami technique is used to construct custom-shaped nanostructures that can be used as components of two-dimensional crystalline structures with user-defined structural patterns.
Yuki Suzuki +3 more
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Watson−Crick Base-Pairing Properties of Tricyclo-DNA
, 2016 Tricyclo-DNA belongs to the family of conformationally restricted oligodeoxynucleotide analogues. It differs structurally from DNA by an additional ethylene bridge between the centers C(3‘) and C(5‘) of the nucleosides, to which a cyclopropane unit is ...
Christian J. Leumann (8129) +1 more
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Identification of binding mechanisms in single molecule-DNA complexes
, 2003 Eckel R, Ros R, Ros A, Wilking SD, Sewald N, Anselmetti D. Identification of binding mechanisms in single molecule-DNA complexes. Biophysical journal. 2003;85(3):1968-1973.Changes in the elastic properties of single deoxyribonucleic acid (DNA) molecules ...
Anselmetti, Dario +14 more
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