Results 41 to 50 of about 804,751 (297)

Bubble propagation in a helicoidal molecular chain

, 2000
We study the propagation of very large amplitude localized excitations in a model of DNA that takes explicitly into account the helicoidal structure. These excitations represent the ``transcription bubble'', where the hydrogen bonds between complementary
A. Campa, A. Campa, Alessandro Campa, D. Cule, D. Poland, G. Gaeta, G. Kalosakas, L. Casetti, L. V. Yakushevich, M. Barbi, M. Peyrard, M. Remoissenet, M. Salerno, O. Bang, R. Boesch, R. Boesch, R. M. Wartell, R. Rajaraman, R. S. MacKay, S. A. Gredeskul, S. Aubry, S. Aubry, S. Cocco, S. Flach, S. Flach, T. Dauxois, T. Dauxois, T. Dauxois, Y. S. Kivshar, Y. Z. Chen, Y. Zhang   +30 more
core   +1 more source

Xeroderma Pigmentosum Group C Deficiency Alters Cigarette Smoke DNA Damage Cell Fate and Accelerates Emphysema Development [PDF]

, 2018
Cigarette smoke (CS) exposure is a major risk factor for the development of emphysema, a common disease characterized by loss of cells comprising the lung parenchyma.
Fisher, Amanda J., Justice, Matthew J., Lamb, Isaac, Petrache, Irina, Saliba, Jacob, Schweitzer, Kelly S., Sears, Catherine R., Wicker, Jessica, Zhou, Huaxin   +8 more
core   +1 more source

Why are complementary DNA strands symmetric? [PDF]

Bioinformatics, 2002
Abstract Motivation: Over sufficiently long windows, complementary strands of DNA tend to have the same base composition. A few reports have indicated that this first-order parity rule extends at higher orders to oligonucleotide composition, at least in some organisms or taxa. However, the scientific literature falls short of providing a
Pierre-François, Baisnée, Steve, Hampson, Pierre, Baldi   +2 more
openaire   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Phase Transition of DNA-Linked Gold Nanoparticle

, 2002
Melting and hybridization of DNA-capped gold nanoparticle networks are investigated with optical absorption spectroscopy. Single-stranded, 12-base DNA-capped gold nanoparticles are linked with complementary, single-stranded, 24-base linker DNA to form ...
Ching-Hwa Kiang, Chrisey, Cule, Deem, Elghanian, Gelfand, Goddard, Lazarides, Link, Mirkin, Rudnick, Rudnick, Storhoff, Storhoff, Wartell   +14 more
core   +1 more source

Preparation of fluorescent DNA probe by solid-phase organic synthesis

eXPRESS Polymer Letters, 2009
Fluorescent DNA probe based on fluorescence resonance energy transfer (FRET) was prepared by solid-phase organic synthesis when CdTe quantum dots (QDs) were as energy donors and Au nanoparticles (AuNPs) were as energy accepters.
doaj   +1 more source

Colloidal Flying Carpets [PDF]

, 2009
DNA plays a special role in polymer science not just because of the highly selective recognition of complementary single DNA strands but also because bacteria can express DNA chains that are very long yet perfectly monodisperse.
Eiser, Erika, Geerts, Nienke
core   +1 more source

DNA Renaturation at the Water-Phenol Interface [PDF]

, 2003
We study DNA adsorption and renaturation in a water-phenol two-phase system, with or without shaking. In very dilute solutions, single-stranded DNA is adsorbed at the interface in a salt-dependent manner.
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core   +4 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Factors Impacting Invader-Mediated Recognition of Double-Stranded DNA

Molecules, 2022
The development of chemically modified oligonucleotides enabling robust, sequence-unrestricted recognition of complementary chromosomal DNA regions has been an aspirational goal for scientists for many decades.
Caroline P. Shepard, Raymond G. Emehiser, Saswata Karmakar, Patrick J. Hrdlicka   +3 more
doaj   +1 more source